Clinical and virologic characteristics of 137 patients who underwent autologous hematopoietic cell transplantation
| Characteristic . | Values . |
|---|---|
| Sex: M/F | 72 (53)/65 (47) |
| Median age, y (range) | 37 (1-67) |
| Transplantation ALT | |
| Elevated | 6 (4) |
| Normal | 131 (96) |
| Pretransplant hepatitis serologic results | |
| HBsAg positive | 23 (17) |
| HBeAg positive | 4 (3) |
| HBeAb positive | 19 (14) |
| HBV DNA positive on Digene assay | 10 (7) |
| HBsAg, HBsAb, and HBcAb negative | 77 (56) |
| Precore A1896 variants alone present | 2 (1) |
| BCP T1762/A1764variant alone present | 3 (2) |
| Both A1896 and T1762/A1764 variants present | 3 (2) |
| Anti-HBs positive/anti-HBc positive | 37/28 (27/20) |
| HBV DNA positive by PCR | 41 (30) |
| HBV genotype B/HBV genotype C | 22/18 (16/13) |
| Anti-HCV positive | 1 (1) |
| Underlying disease | |
| Non-Hodgkin lymphoma | 60 (44) |
| Breast cancer | 18 (13) |
| Multiple myeloma | 17 (12) |
| Hodgkin lymphoma | 11 (8) |
| Other | 31 (23) |
| Characteristic . | Values . |
|---|---|
| Sex: M/F | 72 (53)/65 (47) |
| Median age, y (range) | 37 (1-67) |
| Transplantation ALT | |
| Elevated | 6 (4) |
| Normal | 131 (96) |
| Pretransplant hepatitis serologic results | |
| HBsAg positive | 23 (17) |
| HBeAg positive | 4 (3) |
| HBeAb positive | 19 (14) |
| HBV DNA positive on Digene assay | 10 (7) |
| HBsAg, HBsAb, and HBcAb negative | 77 (56) |
| Precore A1896 variants alone present | 2 (1) |
| BCP T1762/A1764variant alone present | 3 (2) |
| Both A1896 and T1762/A1764 variants present | 3 (2) |
| Anti-HBs positive/anti-HBc positive | 37/28 (27/20) |
| HBV DNA positive by PCR | 41 (30) |
| HBV genotype B/HBV genotype C | 22/18 (16/13) |
| Anti-HCV positive | 1 (1) |
| Underlying disease | |
| Non-Hodgkin lymphoma | 60 (44) |
| Breast cancer | 18 (13) |
| Multiple myeloma | 17 (12) |
| Hodgkin lymphoma | 11 (8) |
| Other | 31 (23) |
Values are numbers (%) of patients unless otherwise specified.
ALT indicates alanine aminotransferase; HBsAg, hepatitis B (HB) surface antigen; HBeAg, HB e antigen; HBeAb, HB e antibody; HBV, HB virus; HBsAb, HB surface antibody; HBcAb, HB core antibody; BCP, basic core promoter; HBs, HB surface; HBc, HB core; PCR, polymerase chain reaction; and HCV, hepatitis C.