Table 1. Summary of morphologic findings... | American Society of Hematology

Table 1.

Summary of morphologic findings

Mouse	Spleen red pulp	Spleen total cell no.^*	Spleen weight (mg)	Liver EMH	Liver iron
Hbb^+/+	Area 40%-50%; nRBCs ≤ 20%	190 ± 21	113 ± 21	None	0
Hbb^th3/+	Area 70%-90%; nRBCs 80%-90%	509 ± 69	383 ± 33	Marked^†	1 -3+
Hbb^th3/+-GFP	Area 70%-90%; nRBCs 80%-90%	465 ± 99	343 ± 15	Moderate	1 -4+
Hbb^th3/+-TNS9	Area 50%-60%; nRBCs 20%-70%	204 ± 37	120 ± 27	None	0 -1+

Mouse	Spleen red pulp	Spleen total cell no.^*	Spleen weight (mg)	Liver EMH	Liver iron
Hbb^+/+	Area 40%-50%; nRBCs ≤ 20%	190 ± 21	113 ± 21	None	0
Hbb^th3/+	Area 70%-90%; nRBCs 80%-90%	509 ± 69	383 ± 33	Marked^†	1 -3+
Hbb^th3/+-GFP	Area 70%-90%; nRBCs 80%-90%	465 ± 99	343 ± 15	Moderate	1 -4+
Hbb^th3/+-TNS9	Area 50%-60%; nRBCs 20%-70%	204 ± 37	120 ± 27	None	0 -1+

nRBCs indicates nucleated red blood cells.

Cell number × 10⁶.

Two of 3 Hbb^th3/+ mice showed EMH.