Distribution of patient characteristics by treatment assignment
| Patient characteristic . | Native ASNase (%) . | Pegaspargase (%) . |
|---|---|---|
| Total | 59 (100) | 59 (100) |
| Age | ||
| 1-2 y | 20 (34) | 11 (19) |
| 3-5 y | 18 (30) | 26 (44) |
| 6-9 y | 21 (36) | 22 (37) |
| Sex | ||
| Male | 33 (56) | 31 (53) |
| Female | 26 (44) | 28 (47) |
| Race | ||
| White | 39 (66) | 38 (64) |
| Nonwhite | 20 (34) | 21 (36) |
| WBC count at diagnosis | ||
| Below 20 000 | 46 (78) | 47 (80) |
| Above 20 000 | 13 (22) | 12 (20) |
| CALLA+ | 53 (90) | 50 (85) |
| Platelet count at diagnosis | ||
| Below 50 000 | 30 (51) | 20 (34) |
| 50 000 to 149 000 | 19 (32) | 21 (36) |
| Above 150 000 | 10 (17) | 18 (30) |
| Hemoglobin level | ||
| Below 8 | 24 (41) | 30 (52) |
| 8-11 | 29 (49) | 22 (38) |
| Above 11 | 6 (10) | 6 (10) |
| CNS disease | ||
| More than 5 cells/μL, positive cytology | 0 (0) | 0 (0) |
| Less than 5 cells/μL, positive cytology | 9 (15) | 4 (7) |
| Less than 5 cells/μL, negative cytology | 46 (78) | 52 (88) |
| Mediastinal mass less than thoracic diameter | 6 (10) | 4 (7) |
| Hepatomegaly, edge below the umbilicus | 2 (3) | 4 (7) |
| Splenomegaly, edge below the umbilicus | 3 (5) | 3 (5) |
| Lymphadenopathy, massive | 1 (2) | 1 (2) |
| Patient characteristic . | Native ASNase (%) . | Pegaspargase (%) . |
|---|---|---|
| Total | 59 (100) | 59 (100) |
| Age | ||
| 1-2 y | 20 (34) | 11 (19) |
| 3-5 y | 18 (30) | 26 (44) |
| 6-9 y | 21 (36) | 22 (37) |
| Sex | ||
| Male | 33 (56) | 31 (53) |
| Female | 26 (44) | 28 (47) |
| Race | ||
| White | 39 (66) | 38 (64) |
| Nonwhite | 20 (34) | 21 (36) |
| WBC count at diagnosis | ||
| Below 20 000 | 46 (78) | 47 (80) |
| Above 20 000 | 13 (22) | 12 (20) |
| CALLA+ | 53 (90) | 50 (85) |
| Platelet count at diagnosis | ||
| Below 50 000 | 30 (51) | 20 (34) |
| 50 000 to 149 000 | 19 (32) | 21 (36) |
| Above 150 000 | 10 (17) | 18 (30) |
| Hemoglobin level | ||
| Below 8 | 24 (41) | 30 (52) |
| 8-11 | 29 (49) | 22 (38) |
| Above 11 | 6 (10) | 6 (10) |
| CNS disease | ||
| More than 5 cells/μL, positive cytology | 0 (0) | 0 (0) |
| Less than 5 cells/μL, positive cytology | 9 (15) | 4 (7) |
| Less than 5 cells/μL, negative cytology | 46 (78) | 52 (88) |
| Mediastinal mass less than thoracic diameter | 6 (10) | 4 (7) |
| Hepatomegaly, edge below the umbilicus | 2 (3) | 4 (7) |
| Splenomegaly, edge below the umbilicus | 3 (5) | 3 (5) |
| Lymphadenopathy, massive | 1 (2) | 1 (2) |
WBC indicates white blood cell; CALLA+, reactive to common ALL antigen; Hbg, hemoglobin; CNS, central nervous system.