Characteristics of the initial population of consecutive women from which the studied final groups of childless patients and controls were obtained after exclusion of those with thrombotic antecedents and/or biologic prothrombotic factors
. | N . | TA . | AT . | PC . | PS . | FVL . | FIIL . | aPLAb . | HCY . | PAI-1 . |
---|---|---|---|---|---|---|---|---|---|---|
Group 1 | ||||||||||
N | 289 | 15 | 0 | 0 | 0 | 5 | 6 | 46 | 26 | 55 |
% | 5.2 | 0 | 0 | 0 | 1.7 | 2.1 | 15.9 | 9 | 19 | |
Group 2 | ||||||||||
N | 312 | 27 | 0 | 1 | 12 | 20 | 13 | 51 | 23 | 27 |
% | 8.7 | 0 | 0.3 | 3.9 | 6.4 | 4.2 | 16.4 | 7.4 | 8.7 | |
Group 3 | ||||||||||
N | 81 | 8 | 0 | 0 | 3 | 6 | 4 | 15 | 6 | 4 |
% | 9.9 | 0 | 0 | 3.7 | 7.4 | 4.9 | 18.5 | 7.4 | 4.9 | |
Control group | ||||||||||
N | 217 | 1 | 0 | 0 | 0 | 4 | 5 | 2 | 2 | 3 |
% | 0.4 | 0 | 0 | 0 | 1.8 | 2.3 | 0.9 | 0.9 | 1.4 |
. | N . | TA . | AT . | PC . | PS . | FVL . | FIIL . | aPLAb . | HCY . | PAI-1 . |
---|---|---|---|---|---|---|---|---|---|---|
Group 1 | ||||||||||
N | 289 | 15 | 0 | 0 | 0 | 5 | 6 | 46 | 26 | 55 |
% | 5.2 | 0 | 0 | 0 | 1.7 | 2.1 | 15.9 | 9 | 19 | |
Group 2 | ||||||||||
N | 312 | 27 | 0 | 1 | 12 | 20 | 13 | 51 | 23 | 27 |
% | 8.7 | 0 | 0.3 | 3.9 | 6.4 | 4.2 | 16.4 | 7.4 | 8.7 | |
Group 3 | ||||||||||
N | 81 | 8 | 0 | 0 | 3 | 6 | 4 | 15 | 6 | 4 |
% | 9.9 | 0 | 0 | 3.7 | 7.4 | 4.9 | 18.5 | 7.4 | 4.9 | |
Control group | ||||||||||
N | 217 | 1 | 0 | 0 | 0 | 4 | 5 | 2 | 2 | 3 |
% | 0.4 | 0 | 0 | 0 | 1.8 | 2.3 | 0.9 | 0.9 | 1.4 |
Group 1, patients with 3 unexplained primary miscarriages before the 8th week of gestation; group 2, patients with one unexplained primary episode of early fetal death from the 10th to the end of the 19th week of gestation; group 3, patients with one unexplained primary episode of late fetal death from the beginning of the 20th week of gestation; control group, healthy mothers of one child. TA, thrombotic antecedents; AT, antithrombin deficiency; PC, protein C deficiency; PS, protein S deficiency; FVL, factor V Leiden mutation; FIIL, allele 20210A in the prothrombin gene; aPLAb, antiphospholipid/antiprotein antibodies; HCY, mild hyperhomocysteinemia; PAI-1, high plasminogen activator inhibitor 1 plasma levels; all these biologic data are according to previously published methods and results.6-9