Table 1. HLA class II alleles and TCR Vβ... | American Society of Hematology

Table 1.

HLA class II alleles and TCR Vβ gene segments oligoclonally expanded after stimulation with β₂GPI in patients with APS and in healthy responders

Study subjects	Age (y)/sex	Diagnosis	HLA class II alleles				TCR Vβ oligoclonally expanded after β₂-GPI stimulation^*
Study subjects	Age (y)/sex	Diagnosis	DRB1	DRB4	DQB1	DPB1	TCR Vβ oligoclonally expanded after β₂-GPI stimulation^*
APS patients
APS2	35/F	P-APS	^0405/^1202	^*0103	^0301/^0401	^0201/^0501	7
APS3	39/F	P-APS	^1502/^0901	^*0103	^0601/^0303	^0501/^0901	1,7, 13.1, 24
APS4	40/F	SLE-APS	^1501/^0403	^*0103	^0602/^0302	^*0201	5.1,7
APS8	28/F	SLE-APS	^1101/^0901	^*0103	^0301/^0303	^*0501	4,8, 15
APS12	56/F	P-APS	^*0406	^*0103	^*0302	^*0501	3,7, 8
Healthy subjects
HD2	37/M		^0803/^0901	^*0103	^0601/^0303	^*0501	8,22
HD4	45/M		^0101/^0403	^*0103	^0501/^0302	^*0501	7, 8, 13.1, 21
HD11	39/F		^0406/^1201	^*0103	^0301/^0302	^0201/^0501	7,12, 18

Study subjects	Age (y)/sex	Diagnosis	HLA class II alleles				TCR Vβ oligoclonally expanded after β₂-GPI stimulation^*
Study subjects	Age (y)/sex	Diagnosis	DRB1	DRB4	DQB1	DPB1	TCR Vβ oligoclonally expanded after β₂-GPI stimulation^*
APS patients
APS2	35/F	P-APS	^0405/^1202	^*0103	^0301/^0401	^0201/^0501	7
APS3	39/F	P-APS	^1502/^0901	^*0103	^0601/^0303	^0501/^0901	1,7, 13.1, 24
APS4	40/F	SLE-APS	^1501/^0403	^*0103	^0602/^0302	^*0201	5.1,7
APS8	28/F	SLE-APS	^1101/^0901	^*0103	^0301/^0303	^*0501	4,8, 15
APS12	56/F	P-APS	^*0406	^*0103	^*0302	^*0501	3,7, 8
Healthy subjects
HD2	37/M		^0803/^0901	^*0103	^0601/^0303	^*0501	8,22
HD4	45/M		^0101/^0403	^*0103	^0501/^0302	^*0501	7, 8, 13.1, 21
HD11	39/F		^0406/^1201	^*0103	^0301/^0302	^0201/^0501	7,12, 18

TCR Vβ segments detected in 2 or more subjects are shown in bold.

P-APS, primary APS; SLE-APS, secondary APS accompanied by systemic lupus erythematosus.