Univariate analysis of prognostic factors for survival after BT
Factor . | No. . | Median survival (95% CI) . | P . |
---|---|---|---|
Patient age, y | |||
50 or younger | 49 | 8.8 (7-10) | .04 |
Older than 50 | 25 | 5.5 (4-7) | |
WBC count at BT, × 109/L | |||
No higher than 60 | 43 | 8.7 (5-12) | .04 |
Higher than 60 | 19 | 5.6 (3-8) | |
PB blasts at BT, % | |||
No more than 50 | 35 | 8.2 (6-10) | .025 |
More than 50 | 15 | 3.6 (0-7) | |
Cytogenetic evolution | |||
No | 24 | 11.8 (9-15) | .012 |
Yes | 50 | 6.3 (5-7) | |
Response to first/second therapy | |||
CP | 34 | 13 (10-17) | .00001 |
No CP | 40 | 5.7 (5-7) | |
Pre-BT treatment | |||
No more than 2 agents | 37 | 8.7 (6-11) | .05 |
More than 2 agents | 35 | 6.8 (5-8) | |
SCT | |||
Yes | 37 | 11 (8-14) | .039 |
No | 37 | 6.8 (5-8) | |
Type of SCT | |||
Allo | 23 | 11.6 (10.7-12.5) | .024 |
Auto | 14 | 5.8 (3.5-8) |
Factor . | No. . | Median survival (95% CI) . | P . |
---|---|---|---|
Patient age, y | |||
50 or younger | 49 | 8.8 (7-10) | .04 |
Older than 50 | 25 | 5.5 (4-7) | |
WBC count at BT, × 109/L | |||
No higher than 60 | 43 | 8.7 (5-12) | .04 |
Higher than 60 | 19 | 5.6 (3-8) | |
PB blasts at BT, % | |||
No more than 50 | 35 | 8.2 (6-10) | .025 |
More than 50 | 15 | 3.6 (0-7) | |
Cytogenetic evolution | |||
No | 24 | 11.8 (9-15) | .012 |
Yes | 50 | 6.3 (5-7) | |
Response to first/second therapy | |||
CP | 34 | 13 (10-17) | .00001 |
No CP | 40 | 5.7 (5-7) | |
Pre-BT treatment | |||
No more than 2 agents | 37 | 8.7 (6-11) | .05 |
More than 2 agents | 35 | 6.8 (5-8) | |
SCT | |||
Yes | 37 | 11 (8-14) | .039 |
No | 37 | 6.8 (5-8) | |
Type of SCT | |||
Allo | 23 | 11.6 (10.7-12.5) | .024 |
Auto | 14 | 5.8 (3.5-8) |