Table 1.

Chemotherapy regimens used to treat BT

RegimenNo. of patients
AML-like 
 Daunorubicin, cytarabine, 6-thioguanine (DAT); mitoxantrone, cytarabine, etoposide (MAE); cytarabine, daunorubicin, etoposide (ADE)  
ALL-like 16  
 Vincristine, daunorubicin, prednisolone l-asparaginase, Intrathecal MTX under UKALL or MRC protocol  
FLAG-IDA 4  
 Fludarabine, high-dose cytarabine, G-CSF, idarubucin  
Other combinations 
 Idarubicin, cytarabine, etoposide (ICE), carboplatin, mitoxantrone, cytarabine; mitoxantrone, cytarabine; cytarabine, interferon; 6-thioguanine, hydroxyurea, interferon; mitoxantrone, hydroxyurea  
Single agents 5  
 Mitoxantrone, 6-mercaptopurine, etoposide  
RegimenNo. of patients
AML-like 
 Daunorubicin, cytarabine, 6-thioguanine (DAT); mitoxantrone, cytarabine, etoposide (MAE); cytarabine, daunorubicin, etoposide (ADE)  
ALL-like 16  
 Vincristine, daunorubicin, prednisolone l-asparaginase, Intrathecal MTX under UKALL or MRC protocol  
FLAG-IDA 4  
 Fludarabine, high-dose cytarabine, G-CSF, idarubucin  
Other combinations 
 Idarubicin, cytarabine, etoposide (ICE), carboplatin, mitoxantrone, cytarabine; mitoxantrone, cytarabine; cytarabine, interferon; 6-thioguanine, hydroxyurea, interferon; mitoxantrone, hydroxyurea  
Single agents 5  
 Mitoxantrone, 6-mercaptopurine, etoposide  

UKALL indicates United Kingdom Acute Lymphoid Leukaemia; MRC, Medical Research Council.

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