Outcome and patient characteristics according to number of joint bleeds until start of prophylaxis
| No. of joint bleeds until start of prophylaxis . | Less than 3 . | 3-14 . | 15-44 . | 45 or more . |
|---|---|---|---|---|
| Patients | ||||
| No. | 10 | 11 | 13 | 9 |
| Age at last Pettersson score, y | 15.8 (14.1-17.0) | 17.5 (13.9-20.8) | 17.2 (14.3-22.9) | 22.3 (16.2-26.6) |
| Age at first joint bleed, y | 1.0 (1.0-1.3) | 1.4 (0.8-3.5) | 2.4 (1.8-2.7) | 3.0 (2.3-3.7) |
| Treatment | ||||
| Age at start of prophylaxis, y | 1.4 (1.1-2.6) | 4.1 (2.4-5.0) | 5.6 (5.1-6.9) | 8.7 (8.3-16.7) |
| Lag time, y | − 0.2 (−1.8-+ 0.3) | 1.6 (1.4-2.6) | 3.5 (2.6-4.6) | 7.1 (4.8-13.7) |
| No. of joint bleeds until prophylaxis | 0.5 (0-1) | 11 (7-13) | 32 (24-42) | 100 (81-132) |
| Outcome | ||||
| Last Pettersson score (maximum 78) | 0 (0-2) | 5 (3-13) | 7 (0-17) | 8 (4-14) |
| Pts with last Pettersson above 0, % | 30 | 82 | 69 | 78 |
| Clinical score (maximum 90)3-150 | 0 (0-1) | 2 (0-5) | 4 (1-6) | 4 (0-5) |
| Pts with clinical score above 0, % | 30 | 73 | 77 | 67 |
| No. of joint bleeds until start of prophylaxis . | Less than 3 . | 3-14 . | 15-44 . | 45 or more . |
|---|---|---|---|---|
| Patients | ||||
| No. | 10 | 11 | 13 | 9 |
| Age at last Pettersson score, y | 15.8 (14.1-17.0) | 17.5 (13.9-20.8) | 17.2 (14.3-22.9) | 22.3 (16.2-26.6) |
| Age at first joint bleed, y | 1.0 (1.0-1.3) | 1.4 (0.8-3.5) | 2.4 (1.8-2.7) | 3.0 (2.3-3.7) |
| Treatment | ||||
| Age at start of prophylaxis, y | 1.4 (1.1-2.6) | 4.1 (2.4-5.0) | 5.6 (5.1-6.9) | 8.7 (8.3-16.7) |
| Lag time, y | − 0.2 (−1.8-+ 0.3) | 1.6 (1.4-2.6) | 3.5 (2.6-4.6) | 7.1 (4.8-13.7) |
| No. of joint bleeds until prophylaxis | 0.5 (0-1) | 11 (7-13) | 32 (24-42) | 100 (81-132) |
| Outcome | ||||
| Last Pettersson score (maximum 78) | 0 (0-2) | 5 (3-13) | 7 (0-17) | 8 (4-14) |
| Pts with last Pettersson above 0, % | 30 | 82 | 69 | 78 |
| Clinical score (maximum 90)3-150 | 0 (0-1) | 2 (0-5) | 4 (1-6) | 4 (0-5) |
| Pts with clinical score above 0, % | 30 | 73 | 77 | 67 |
Values are numbers or medians (IQR: 25th and 75th percentiles).
The clinical score was assessed within 1 year of the last Pettersson score.