Nucleotide sequence analysis in cases using VH3-21
| Case . | VH gene . | Homology, % . | N—D—N* . | D . | JH . |
|---|---|---|---|---|---|
| 1 | VH3-21 | 96.9 | CGAAAGGAG | — | JH6 |
| 4 | VH3-21 | 99.1 | AGCGGTGATCGCA | — | JH6 |
| 11 | VH3-21 | 95.1 | CAGATCGGAACGCTT | — | JH6 |
| 36 | VH3-21 | 97.3 | GATGCAA | — | JH6 |
| 39 | VH3-21 | 97.3 | GATTATAGCAGCAGCT | D6-13 | JH4 |
| 43 | VH3-21 | 96.4 | CAGATCGTAAT | — | JH6 |
| 46 | VH3-21 | 96.4 | GATGCGAACGC | — | JH6 |
| 51 | VH3-21 | 97.3 | TCGTCGGATAGTAGTGGTG | D3-22 | JH4 |
| 62 | VH3-21 | 97.3 | GATGCAA | — | JH6 |
| 75 | VH3-21 | 97.8 | GACGCAA | — | JH6 |
| 78 | VH3-21 | 100 | GATACTCGGGAAGTCGGGCTACTATGGTTCGG | D3-10 | JH6 |
| 87 | VH3-21 | 97.3 | CGGACCGAA | — | JH6 |
| 93 | VH3-21 | 95.1 | GATGGAGCGGGGGCTATGGTTAATGT | D5-5 | JH3 |
| 103 | VH3-21 | 92.8 | GAATCCCGGTTCGTATAACTGGAACTACGGCTAATACAGGTATACT- TATTTATCGTACTATGACAC | D1-7 | JH6 |
| 113 | VH3-21 | 96.9 | GATGCAA | — | JH6 |
| Case . | VH gene . | Homology, % . | N—D—N* . | D . | JH . |
|---|---|---|---|---|---|
| 1 | VH3-21 | 96.9 | CGAAAGGAG | — | JH6 |
| 4 | VH3-21 | 99.1 | AGCGGTGATCGCA | — | JH6 |
| 11 | VH3-21 | 95.1 | CAGATCGGAACGCTT | — | JH6 |
| 36 | VH3-21 | 97.3 | GATGCAA | — | JH6 |
| 39 | VH3-21 | 97.3 | GATTATAGCAGCAGCT | D6-13 | JH4 |
| 43 | VH3-21 | 96.4 | CAGATCGTAAT | — | JH6 |
| 46 | VH3-21 | 96.4 | GATGCGAACGC | — | JH6 |
| 51 | VH3-21 | 97.3 | TCGTCGGATAGTAGTGGTG | D3-22 | JH4 |
| 62 | VH3-21 | 97.3 | GATGCAA | — | JH6 |
| 75 | VH3-21 | 97.8 | GACGCAA | — | JH6 |
| 78 | VH3-21 | 100 | GATACTCGGGAAGTCGGGCTACTATGGTTCGG | D3-10 | JH6 |
| 87 | VH3-21 | 97.3 | CGGACCGAA | — | JH6 |
| 93 | VH3-21 | 95.1 | GATGGAGCGGGGGCTATGGTTAATGT | D5-5 | JH3 |
| 103 | VH3-21 | 92.8 | GAATCCCGGTTCGTATAACTGGAACTACGGCTAATACAGGTATACT- TATTTATCGTACTATGACAC | D1-7 | JH6 |
| 113 | VH3-21 | 96.9 | GATGCAA | — | JH6 |
D sequences are underlined.