Table 1.

Clinical findings

Patient no.Age/sexInterval between abciximab exposures, wkPlatelet levelDays required to reach 100 × 109/LBleeding symptomsOther
PretreatmentNadir
1 53/F 3 “Normal” 1 × 109/L 9 Petechiae, ecchymoses, gastrointestinal bleeding Emesis and hypotension 15 minutes after infusion was started, abciximab stopped 
2 75/F 15 190 × 109/L 6 × 109/L > 3 Petechiae, oozing from venipuncture sites  
3 45/F 2 “Normal” 4 × 109/L < 5 Petechiae, oozing from venipuncture sites  
4 60/M 3 “Normal” 1 × 109/L 4 Petechiae  
5 63/M 3 142 × 109/L 1 × 109/L 5 Petechiae, oozing from venipuncture sites Had drop in platelets from 199 × 109/L to 139 × 109/L after first treatment 
6 48/M 2 139 × 109/L 6 × 109/L 6 Petechiae, ecchymoses  
7 41/M 6 239 × 109/L 5 × 109/L 4 Petechiae  
8 55/M 2 205 × 109/L 3 × 109/L 7 Petechiae, ecchymoses  
9 60/M 4 150 × 109/L 2 × 109/L 8 Petechia, oozing from venipuncture sites, intrapulmonary hemorrhage Anaphylactic reaction, required mechanical ventilation 
Patient no.Age/sexInterval between abciximab exposures, wkPlatelet levelDays required to reach 100 × 109/LBleeding symptomsOther
PretreatmentNadir
1 53/F 3 “Normal” 1 × 109/L 9 Petechiae, ecchymoses, gastrointestinal bleeding Emesis and hypotension 15 minutes after infusion was started, abciximab stopped 
2 75/F 15 190 × 109/L 6 × 109/L > 3 Petechiae, oozing from venipuncture sites  
3 45/F 2 “Normal” 4 × 109/L < 5 Petechiae, oozing from venipuncture sites  
4 60/M 3 “Normal” 1 × 109/L 4 Petechiae  
5 63/M 3 142 × 109/L 1 × 109/L 5 Petechiae, oozing from venipuncture sites Had drop in platelets from 199 × 109/L to 139 × 109/L after first treatment 
6 48/M 2 139 × 109/L 6 × 109/L 6 Petechiae, ecchymoses  
7 41/M 6 239 × 109/L 5 × 109/L 4 Petechiae  
8 55/M 2 205 × 109/L 3 × 109/L 7 Petechiae, ecchymoses  
9 60/M 4 150 × 109/L 2 × 109/L 8 Petechia, oozing from venipuncture sites, intrapulmonary hemorrhage Anaphylactic reaction, required mechanical ventilation 
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