Correlations between 14q32 chromosomal abnormalities, immunoglobulin types, and clinical presentation in 35 human myeloma cell lines
| . | Rearrangements . | No 14q32 abnormality . | Other 14q32 partners . | ||
|---|---|---|---|---|---|
| CCND1 . | FGFR3 . | c-maf . | |||
| Primary PCL (n = 10) | 3 | 0 | 4 (P < .08)4-150 | 1 | 2 |
| Multiple myeloma (n = 25) | 8 | 8 | 3 | 2 | 4 |
| IgG type (n = 11) | 2 | 2 | 3 | 2 | 2 |
| IgA type (n = 12) | 1 | 5 (P < .09)4-150 | 3 | 1 | 2 |
| BJ type (n = 9) | 6 (P < .04)4-150 | 1 | 1 | 0 | 1 |
| Other (IgE or nonsecretory) | 2 | 0 | 0 | 0 | 1 |
| . | Rearrangements . | No 14q32 abnormality . | Other 14q32 partners . | ||
|---|---|---|---|---|---|
| CCND1 . | FGFR3 . | c-maf . | |||
| Primary PCL (n = 10) | 3 | 0 | 4 (P < .08)4-150 | 1 | 2 |
| Multiple myeloma (n = 25) | 8 | 8 | 3 | 2 | 4 |
| IgG type (n = 11) | 2 | 2 | 3 | 2 | 2 |
| IgA type (n = 12) | 1 | 5 (P < .09)4-150 | 3 | 1 | 2 |
| BJ type (n = 9) | 6 (P < .04)4-150 | 1 | 1 | 0 | 1 |
| Other (IgE or nonsecretory) | 2 | 0 | 0 | 0 | 1 |
Ig indicates immunoglobulin. See Tables 1 and 2 for other abbreviations.
P values were calculated for all cases with 14q32 abnormalities.