CMV disease and overall mortality in the first 180 days after allogeneic SCT among patients who received preemptive treatment for CMV infection with either foscarnet or ganciclovir
. | Foscarnet n = 110 . | Ganciclovir n = 103 . |
---|---|---|
Patients with CMV disease | 5 | 5 |
Type of CMV disease | ||
Pneumonia | 3 | 23-150 |
Gastrointestinal | 2 | 2 |
Retinitis | 0 | 1 |
Median time to CMV disease, d (range) | ||
From SCT | 62 (50-177) | 93 (43-168) |
From randomized treatment start | 31 (8-126) | 42 (3-128) |
Overall mortality (%) | 29 (26) | 23 (22) |
Median time from SCT to death from any cause, d (range) | 118 (39-179) | 85 (43-155) |
. | Foscarnet n = 110 . | Ganciclovir n = 103 . |
---|---|---|
Patients with CMV disease | 5 | 5 |
Type of CMV disease | ||
Pneumonia | 3 | 23-150 |
Gastrointestinal | 2 | 2 |
Retinitis | 0 | 1 |
Median time to CMV disease, d (range) | ||
From SCT | 62 (50-177) | 93 (43-168) |
From randomized treatment start | 31 (8-126) | 42 (3-128) |
Overall mortality (%) | 29 (26) | 23 (22) |
Median time from SCT to death from any cause, d (range) | 118 (39-179) | 85 (43-155) |
CMV indicates cytomegalovirus; SCT, stem cell transplantation.
Fatal in both cases.