Success rate of human thymopoiesis according to mouse strain and conditioning
| N (mice) . | NOD/SCID RT . | NOD/SCID RT + TM-β1 . | Rag2−/−γc−/− mice RT . |
|---|---|---|---|
| Total | 28 | 39 | 25 |
| DP in thymus (no.) | 5 | 22 | 4 |
| Success rate (%) | 18 | 56 | 6 |
| N (mice) . | NOD/SCID RT . | NOD/SCID RT + TM-β1 . | Rag2−/−γc−/− mice RT . |
|---|---|---|---|
| Total | 28 | 39 | 25 |
| DP in thymus (no.) | 5 | 22 | 4 |
| Success rate (%) | 18 | 56 | 6 |
Comparison of thymus repopulation frequency between irradiated NOD/SCID mice (RT), irradiated NOD/SCID mice pretreated with injection of TM-β1 (RT + TM-β1), and irradiated Rag2−/−γc−/− mice (RT). Of each group, the total number of mice and number/percentage of mice having DP (≥ 5%) in their thymi are shown.