Flow-cytometric data in patients with RA after anti-TNFα treatment
| . | Before treatment (n = 10) . | After treatment (n = 10) . | P . |
|---|---|---|---|
| BMMC fraction | |||
| % CD34+cells | 1.21 ± 0.403-150 | 2.03 ± 0.73 | .003 |
| (1.20, 0.60-1.80) | (2.00, 0.70-3.50) | ||
| % CD34+/CD38+cells | 0.86 ± 0.39 | 1.72 ± 0.66 | .004 |
| (0.86, 0.20-1.40) | (1.75, 0.60-3.20) | ||
| % CD34+/CD38−cells | 0.34 ± 0.18 | 0.31 ± 0.24 | .696 |
| (0.32, 0.10-0.70) | (0.25, 0.10-0.90) | ||
| CD34+ cell fraction | |||
| % Fas+ cells | 16.20 ± 7.26 | 10.87 ± 6.25 | .029 |
| (15.48, 5.60-25.70) | (10.15, 2.60-19.60) | ||
| % 7AADdimcells | 16.09 ± 10.57 | 8.31 ± 5.65 | .016 |
| (13.85, 3.30-32.07) | (6.30, 2.80-18.60) | ||
| CD34+/Fas+ cell fraction | |||
| % 7AADdimcells | 43.94 ± 21.07 | 24.84 ± 16.87 | .009 |
| (39.87, 12.30-73.70) | (19.95, 8.70-58.10) | ||
| CD34+/Fas− cell fraction | |||
| % 7AADdimcells | 7.69 ± 6.15 | 7.79 ± 5.30 | .972 |
| (6.40, 2.90-24.08) | (7.25, 2.30, 17.0) |
| . | Before treatment (n = 10) . | After treatment (n = 10) . | P . |
|---|---|---|---|
| BMMC fraction | |||
| % CD34+cells | 1.21 ± 0.403-150 | 2.03 ± 0.73 | .003 |
| (1.20, 0.60-1.80) | (2.00, 0.70-3.50) | ||
| % CD34+/CD38+cells | 0.86 ± 0.39 | 1.72 ± 0.66 | .004 |
| (0.86, 0.20-1.40) | (1.75, 0.60-3.20) | ||
| % CD34+/CD38−cells | 0.34 ± 0.18 | 0.31 ± 0.24 | .696 |
| (0.32, 0.10-0.70) | (0.25, 0.10-0.90) | ||
| CD34+ cell fraction | |||
| % Fas+ cells | 16.20 ± 7.26 | 10.87 ± 6.25 | .029 |
| (15.48, 5.60-25.70) | (10.15, 2.60-19.60) | ||
| % 7AADdimcells | 16.09 ± 10.57 | 8.31 ± 5.65 | .016 |
| (13.85, 3.30-32.07) | (6.30, 2.80-18.60) | ||
| CD34+/Fas+ cell fraction | |||
| % 7AADdimcells | 43.94 ± 21.07 | 24.84 ± 16.87 | .009 |
| (39.87, 12.30-73.70) | (19.95, 8.70-58.10) | ||
| CD34+/Fas− cell fraction | |||
| % 7AADdimcells | 7.69 ± 6.15 | 7.79 ± 5.30 | .972 |
| (6.40, 2.90-24.08) | (7.25, 2.30, 17.0) |
Median and range values are indicated in parentheses. Statistical analysis was performed using the Student t test for paired samples. P value ≤ .05 was considered statistically significant.
BMMC indicates bone marrow mononuclear cells.
All values are expressed as means ± SD.