Summary of patient samples examined for C/EBPα mutations
| Tumor type . | No. . | P1* . | P2† . | Mutations . |
|---|---|---|---|---|
| AML | 78 | 10 | — | 8‡ |
| MDS | 92 | 14 | — | 2‡ |
| ALL | 23 | — | 1 | — |
| NHL | 34 | — | — | — |
| Lung (nonsmall cell) | 36 | 6 | — | 1 |
| Osteosarcomas | 20 | — | — | — |
| Other sarcomas | 52 | 13 | 4 | — |
| Breast | 22 | 1 | 2 | — |
| Prostate | 33 | 5 | 2 | 1 |
| Glioblastoma | 12 | 4 | — | — |
| Hepatoma | 6 | 2 | — | — |
| Total | 408 | 55 | 9 | 12 |
| Tumor type . | No. . | P1* . | P2† . | Mutations . |
|---|---|---|---|---|
| AML | 78 | 10 | — | 8‡ |
| MDS | 92 | 14 | — | 2‡ |
| ALL | 23 | — | 1 | — |
| NHL | 34 | — | — | — |
| Lung (nonsmall cell) | 36 | 6 | — | 1 |
| Osteosarcomas | 20 | — | — | — |
| Other sarcomas | 52 | 13 | 4 | — |
| Breast | 22 | 1 | 2 | — |
| Prostate | 33 | 5 | 2 | 1 |
| Glioblastoma | 12 | 4 | — | — |
| Hepatoma | 6 | 2 | — | — |
| Total | 408 | 55 | 9 | 12 |
A minus sign (−) indicates that none of the samples contained either a mutation or polymorphism.
P1 indicates polymorphism 1; P2, polymorphism 2; AML, acute myelogenous leukemia; MDS, myelodysplastic syndrome; ALL, acute lymphoblastic leukemia; and NHL, non-Hodgkin lymphoma.
836T > G.
836T > G, 839C > G, 902G > T.
One patient sample contained 2 mutant alleles.