IDUA levels in MPS-1H fibroblasts exposed to different conditioned media (μM/g.h)
| Conditioned medium . | Fresh medium . | Normal MSCs . | MPS-IH MSCs . | Transduced MPS-IH MSCs . | Transduced MPS-IH MSCs + m-6-p . | Transduced MPS-IH MSCs + g-6-p . |
|---|---|---|---|---|---|---|
| MPS-IH fibroblasts | 0 | 1.5 | 0 | 208.9 | 4.9 | 360.7 |
| Normal fibroblasts | 71.9 | nd | nd | nd | nd | nd |
| Conditioned medium . | Fresh medium . | Normal MSCs . | MPS-IH MSCs . | Transduced MPS-IH MSCs . | Transduced MPS-IH MSCs + m-6-p . | Transduced MPS-IH MSCs + g-6-p . |
|---|---|---|---|---|---|---|
| MPS-IH fibroblasts | 0 | 1.5 | 0 | 208.9 | 4.9 | 360.7 |
| Normal fibroblasts | 71.9 | nd | nd | nd | nd | nd |
m-6-p indicates mannose-6-phosphate; g-6-p, glucose-6-phosphate.