Subregional stromal support of LTC-CFCs
| E11 subregion . | Supportive primary lines/ tested (%) . | Supportive clones/tested (%) . | Total supportive (%) . |
|---|---|---|---|
| AM | 0/5 (0) | 4/13 (31) | 4/18 (22) |
| UG | 1/4 (25) | 9/22 (41) | 10/26 (38) |
| EL | 0/6 (0) | 1/18 (6) | 1/24 (4) |
| GI | 1/5 (20) | 2/4 (50) | 3/9 (33) |
| E11 subregion . | Supportive primary lines/ tested (%) . | Supportive clones/tested (%) . | Total supportive (%) . |
|---|---|---|---|
| AM | 0/5 (0) | 4/13 (31) | 4/18 (22) |
| UG | 1/4 (25) | 9/22 (41) | 10/26 (38) |
| EL | 0/6 (0) | 1/18 (6) | 1/24 (4) |
| GI | 1/5 (20) | 2/4 (50) | 3/9 (33) |
Results are a summary of data presented in Figure 1 and data obtained from the primary cell lines before cloning. “Supportive” refers to the stromal cells that, after a 4-week coculture, supported more than 200 CFCs per 104 input BM cells.
LTC-CFCs indicates long-term culture colony-forming cells; E11, embryonic day 11; AM, dorsal aorta and mesenchyme; UG, urogenital ridge; EL, embryonic liver; and GI, gastrointestinal region.