Phenotypic reconstitution of mononuclear cell subsets 3 months and 12 months after transplantation
. | BMT, cells/μL . | PBSCT, cells/μL . | P . |
---|---|---|---|
3 months after transplantation3-150 | |||
CD3+CD4+T cells | 71.3 ± 49 | 182.2 ± 111 | < .001 |
CD3+CD4+CD45RA+ T cells | 11.2 ± 13.4 | 44.6 ± 41.0 | < .002 |
CD3+CD4+CD45R0+ T cells | 59.8 ± 43.7 | 124.3 ± 75.7 | < .03 |
CD3+CD8+ T cells | 274 ± 442 | 515 ± 563 | NS |
CD4/CD8 ratio | 0.48 ± 0.8 | 0.66 ± 0.6 | NS |
CD19+ B cells | 18.1 ± 86 | 20.4 ± 18 | NS |
Monocytes | 483 ± 322 | 569 ± 286 | NS |
NK cells | 164 ± 118 | 167 ± 131 | NS |
12 months after transplantation3-151 | |||
CD3+CD4+T cells | 191 ± 138 | 332 ± 188 | < .01 |
CD3+CD4+CD45RA+ T cells | 37.8 ± 42.4 | 85.6 ± 72.8 | < .07 |
CD3+CD4+CD45R0+ T cells | 181 ± 209 | 223 ± 116 | NS |
CD3+CD8+ T cells | 500 ± 517 | 548 ± 425 | NS |
CD4/CD8 ratio | 0.75 ± 0.8 | 0.82 ± 0.8 | NS |
CD19+ B cells | 91.2 ± 119 | 87.2 ± 105 | NS |
Monocytes | 475 ± 182 | 640 ± 436 | NS |
NK cells | 137 ± 77 | 186 ± 132 | < .03 |
. | BMT, cells/μL . | PBSCT, cells/μL . | P . |
---|---|---|---|
3 months after transplantation3-150 | |||
CD3+CD4+T cells | 71.3 ± 49 | 182.2 ± 111 | < .001 |
CD3+CD4+CD45RA+ T cells | 11.2 ± 13.4 | 44.6 ± 41.0 | < .002 |
CD3+CD4+CD45R0+ T cells | 59.8 ± 43.7 | 124.3 ± 75.7 | < .03 |
CD3+CD8+ T cells | 274 ± 442 | 515 ± 563 | NS |
CD4/CD8 ratio | 0.48 ± 0.8 | 0.66 ± 0.6 | NS |
CD19+ B cells | 18.1 ± 86 | 20.4 ± 18 | NS |
Monocytes | 483 ± 322 | 569 ± 286 | NS |
NK cells | 164 ± 118 | 167 ± 131 | NS |
12 months after transplantation3-151 | |||
CD3+CD4+T cells | 191 ± 138 | 332 ± 188 | < .01 |
CD3+CD4+CD45RA+ T cells | 37.8 ± 42.4 | 85.6 ± 72.8 | < .07 |
CD3+CD4+CD45R0+ T cells | 181 ± 209 | 223 ± 116 | NS |
CD3+CD8+ T cells | 500 ± 517 | 548 ± 425 | NS |
CD4/CD8 ratio | 0.75 ± 0.8 | 0.82 ± 0.8 | NS |
CD19+ B cells | 91.2 ± 119 | 87.2 ± 105 | NS |
Monocytes | 475 ± 182 | 640 ± 436 | NS |
NK cells | 137 ± 77 | 186 ± 132 | < .03 |
CD3+CD4+ T cells are T-helper cells; CD3+CD4+CD45RA+ T cells, naive T-helper cells; CD3+CD4+CD45R0+ T cells, memory T-helper cells.
NK cells indicate natural killer cells; for other abbreviations, see Table 1.
Number of evaluated patients was 37 in the BMT group and 23 in the PBSCT group.
Number of evaluated patients was 32 in the BMT group and 19 in the PBSCT group.