Effect of granulocyte colony-stimulating factor mobilization on blood counts and apheresis product yields
| Variable . | Control subjects . | SCT subjects . | P . |
|---|---|---|---|
| D4 CD34+, 106/L | 33 (40 ± 28) | 56 (58 ± 35) | .27 |
| D5 CD34+, 106/L | 54 (63 ± 29) | 78 (108 ± 64) | .08 |
| Collection eff, % | 60 (64 ± 16) | 48 (48 ± 12) | .04 |
| TNC, × 109 | 41.7 (40.4 ± 6.8) | 51.1 (46.7 ± 13.4) | .24 |
| CD34+, × 106 | 275 (340 ± 162) | 478 (500 ± 279) | .165 |
| CD3+, × 109 | 12.4 (12.9 ± 5.1) | 16.4 (15.9 ± 4.9) | .236 |
| CFU-GM, × 106 | 14.9 (18.4 ± 13) | 36.7 (42.8 ± 23.6) | .065 |
| CD34+/70 kg, × 106 | 3.9 (4.9 ± 2.3) | 6.8 (7.1 ± 4.0) | .165 |
| Variable . | Control subjects . | SCT subjects . | P . |
|---|---|---|---|
| D4 CD34+, 106/L | 33 (40 ± 28) | 56 (58 ± 35) | .27 |
| D5 CD34+, 106/L | 54 (63 ± 29) | 78 (108 ± 64) | .08 |
| Collection eff, % | 60 (64 ± 16) | 48 (48 ± 12) | .04 |
| TNC, × 109 | 41.7 (40.4 ± 6.8) | 51.1 (46.7 ± 13.4) | .24 |
| CD34+, × 106 | 275 (340 ± 162) | 478 (500 ± 279) | .165 |
| CD3+, × 109 | 12.4 (12.9 ± 5.1) | 16.4 (15.9 ± 4.9) | .236 |
| CFU-GM, × 106 | 14.9 (18.4 ± 13) | 36.7 (42.8 ± 23.6) | .065 |
| CD34+/70 kg, × 106 | 3.9 (4.9 ± 2.3) | 6.8 (7.1 ± 4.0) | .165 |
First 2 values are from peripheral blood; all subsequent values refer to apheresis product. Values are given as median (mean ± SD).
D4 indicates day 4 of mobilization; D5, day 5 of mobilization; Collection eff, collection efficiency; TNC, total nucleated cell; and CFU-GM, granulocyte-macrophage colony-forming unit.