Phosphorylated STAT protein expression in patients with HL
| Case no. . | Diagnosis . | Age, y/sex . | Stage . | P-STAT6+ HRS cells . | P-STAT3+ HRS cells . | P-STAT5+ HRS cells . | EBV LMP-1+ HRS cells . |
|---|---|---|---|---|---|---|---|
| 1 | NSHL | 16/M | IV B | +++ | + | ++ | − |
| 2 | NSHL | 24/F | II A | ++++ | − | − | nd |
| 3 | NSHL | 15/F | II A | + | +++ | − | − |
| 4 | NSHL | 43/M | IV B | +++ | ++++ | − | − |
| 5 | NSHL | 33/M | III B | +++ | ++++ | − | − |
| 6 | NSHL | 30/M | II A | ++++ | ++ | − | − |
| 7 | NSHL | 32/F | II B | +++ | ++++ | − | − |
| 8 | NSHL | 27/F | II A | ++++ | +++ | − | − |
| 9 | NSHL | 22/M | III B | +++ | + | − | +++ |
| 10 | NSHL | 34/M | III A | +++ | +++ | + | − |
| 11 | NSHL | 19/M | III A | ++++ | +++ | − | − |
| 12 | NSHL | 36/M | III B | ++++ | + | − | − |
| 13 | NSHL | 31/F | IV A | ++++ | +++ | − | − |
| 14 | NSHL | na | na | ++++ | nd | nd | nd |
| 15 | NSHL | na | na | + | + | − | nd |
| 16 | NSHL, syn | 64/M | III B | − | − | − | − |
| 17 | NSHL, syn | 20/F | II A | ++++ | +++ | − | − |
| 18 | NSHL, syn | 35/M | I B | ++++ | ++++ | ++ | ++++ |
| 19 | NSHL, syn | 45/M | III A | +++ | +++ | ++++ | − |
| 20 | NSHL, syn | 41/F | II A | ++++ | +++ | − | − |
| 21 | NSHL, syn | 25/M | III B | ++++ | +++ | − | − |
| 22 | MCHL | na | na | ++ | +++ | ++ | ++ |
| 23 | MCHL | na | na | − | ++++ | − | ++++ |
| 24 | MCHL | 28/M | II A | ++++ | ++ | ++ | ++++ |
| 25 | MCHL | 28/M | II B | − | ++ | − | ++++ |
| 26 | MCHL | 42/M | I A | ++ | ++++ | ++++ | +++ |
| 27 | MCHL | 42/F | III A | − | ++ | − | − |
| 28 | MCHL | na/F | II A | + | ++++ | ++ | ++++ |
| 29 | MCHL | 88/M | I A | − | − | − | ++++ |
| 30 | LDHL | 54/F | IV B | − | +++ | − | ++++ |
| 31 | LDHL | 65/M | na | − | − | − | − |
| 32 | LDHL | 72/F | IV B | ++++ | +++ | − | ++++ |
| Case no. . | Diagnosis . | Age, y/sex . | Stage . | P-STAT6+ HRS cells . | P-STAT3+ HRS cells . | P-STAT5+ HRS cells . | EBV LMP-1+ HRS cells . |
|---|---|---|---|---|---|---|---|
| 1 | NSHL | 16/M | IV B | +++ | + | ++ | − |
| 2 | NSHL | 24/F | II A | ++++ | − | − | nd |
| 3 | NSHL | 15/F | II A | + | +++ | − | − |
| 4 | NSHL | 43/M | IV B | +++ | ++++ | − | − |
| 5 | NSHL | 33/M | III B | +++ | ++++ | − | − |
| 6 | NSHL | 30/M | II A | ++++ | ++ | − | − |
| 7 | NSHL | 32/F | II B | +++ | ++++ | − | − |
| 8 | NSHL | 27/F | II A | ++++ | +++ | − | − |
| 9 | NSHL | 22/M | III B | +++ | + | − | +++ |
| 10 | NSHL | 34/M | III A | +++ | +++ | + | − |
| 11 | NSHL | 19/M | III A | ++++ | +++ | − | − |
| 12 | NSHL | 36/M | III B | ++++ | + | − | − |
| 13 | NSHL | 31/F | IV A | ++++ | +++ | − | − |
| 14 | NSHL | na | na | ++++ | nd | nd | nd |
| 15 | NSHL | na | na | + | + | − | nd |
| 16 | NSHL, syn | 64/M | III B | − | − | − | − |
| 17 | NSHL, syn | 20/F | II A | ++++ | +++ | − | − |
| 18 | NSHL, syn | 35/M | I B | ++++ | ++++ | ++ | ++++ |
| 19 | NSHL, syn | 45/M | III A | +++ | +++ | ++++ | − |
| 20 | NSHL, syn | 41/F | II A | ++++ | +++ | − | − |
| 21 | NSHL, syn | 25/M | III B | ++++ | +++ | − | − |
| 22 | MCHL | na | na | ++ | +++ | ++ | ++ |
| 23 | MCHL | na | na | − | ++++ | − | ++++ |
| 24 | MCHL | 28/M | II A | ++++ | ++ | ++ | ++++ |
| 25 | MCHL | 28/M | II B | − | ++ | − | ++++ |
| 26 | MCHL | 42/M | I A | ++ | ++++ | ++++ | +++ |
| 27 | MCHL | 42/F | III A | − | ++ | − | − |
| 28 | MCHL | na/F | II A | + | ++++ | ++ | ++++ |
| 29 | MCHL | 88/M | I A | − | − | − | ++++ |
| 30 | LDHL | 54/F | IV B | − | +++ | − | ++++ |
| 31 | LDHL | 65/M | na | − | − | − | − |
| 32 | LDHL | 72/F | IV B | ++++ | +++ | − | ++++ |
++++ indicates 75% to 100% HRS cells positive; +++, 50% to 74% HRS cells positive; ++, 25% to 49% HRS cells positive; +, 10% to 24% HRS cells positive; −, less than 10% HRS cells positive. nd indicates not done; na, not available; syn, syncytial variant of NSHL.