Results of autologous hematopoietic stem cell transplantation in patients with systemic lupus erythematosus
| Reference . | No. of patients receiving transplants . | Regimen . | Results . | Mortality . |
|---|---|---|---|---|
| Marmont et al199 | 1 | TT/Cy | Clinical remission for more than 3 y, serologic relapse | 0 |
| Burt et al179 183 Traynor et al181 | 9 | Cy/ATG | Clinical remission for up to 4 y, 2 relapsed at 3 y and 3.5 y, respectively | 1/12 mobilized |
| Fouillard et al192 | 1 | BEAM | Clinical remission for 1 y; ANA negative at 6 mo but positive at 9 mo | 0 |
| Rosen et al188 | 3 | Cy/ATG | Complete remission of active disease | 0 |
| Musso et al185 | 1 | Cy/ATG | Posttransplantation low ANA titer and low Coombs positive at 8 mo but anti-ds DNA negative and anticardiolipin antibody negative | 0 |
| Reference . | No. of patients receiving transplants . | Regimen . | Results . | Mortality . |
|---|---|---|---|---|
| Marmont et al199 | 1 | TT/Cy | Clinical remission for more than 3 y, serologic relapse | 0 |
| Burt et al179 183 Traynor et al181 | 9 | Cy/ATG | Clinical remission for up to 4 y, 2 relapsed at 3 y and 3.5 y, respectively | 1/12 mobilized |
| Fouillard et al192 | 1 | BEAM | Clinical remission for 1 y; ANA negative at 6 mo but positive at 9 mo | 0 |
| Rosen et al188 | 3 | Cy/ATG | Complete remission of active disease | 0 |
| Musso et al185 | 1 | Cy/ATG | Posttransplantation low ANA titer and low Coombs positive at 8 mo but anti-ds DNA negative and anticardiolipin antibody negative | 0 |
TT/Cy indicates thiotepa and cyclophosphamide; Cy/ATG, cyclophosphamide and antithymocyte globulin; BEAM, carmustine, etoposide, cytarabine, melphalan; ANA, antinuclear antibody; and anti-ds, anti–double strand DNA antibody.