Table 2. Proportion of bone marrow agar... | American Society of Hematology

Table 2.

Proportion of bone marrow agar colony types stimulated by receptor constructs

Receptor	Colony formation (%)^*
	G		GM		M
	High	Low	High	Low	High	Low
EG-R WT	23	37	69	59	9	4.2
EG-R (Y₇₀₄ → F)	27	40	55	50	19	11
EG-R (Y₇₂₉ → F)	3^†	15^†	67	64	30^†	21^†
EG-R (Y₇₄₄ → F)	15	36	72	59	13	6
EG-R (Y₇₆₄ → F)	19	33	80	62	2	6
EG-R (Y_null)	14	34	58	47	28^†	19^†

Receptor	Colony formation (%)^*
	G		GM		M
	High	Low	High	Low	High	Low
EG-R WT	23	37	69	59	9	4.2
EG-R (Y₇₀₄ → F)	27	40	55	50	19	11
EG-R (Y₇₂₉ → F)	3^†	15^†	67	64	30^†	21^†
EG-R (Y₇₄₄ → F)	15	36	72	59	13	6
EG-R (Y₇₆₄ → F)	19	33	80	62	2	6
EG-R (Y_null)	14	34	58	47	28^†	19^†

SE < 25% in 90% of the colony numbers at high (20 ng/mL) and in 80% of the colony numbers at low (0.75 ng/mL) EGF concentrations.

†

Proportion of colonies stimulated by the receptor mutant is significantly different from those stimulated by the WT receptor at each particular EGF concentration.

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