Survival of patients with CMML according to risk groups based on various scoring systems
| Scoring system . | Risk group . | No. of patients (%) . | No. of deaths . | Percentiles of survival (mo) . | P (log-rank test) . | ||
|---|---|---|---|---|---|---|---|
| 75% . | 50% . | 25% . | |||||
| Bournemouth14 | Low | 92 (45) | 74 | 8 | 18 | 33 | < .01 |
| Intermediate | 102 (50) | 77 | 4 | 8 | 18 | ||
| High | 10 (5) | 9 | 2 | 5 | 11 | ||
| Modified Bournemouth21 | Low | 72 (37) | 58 | 8 | 19 | 33 | .01 |
| High | 124 (63) | 96 | 4 | 8 | 19 | ||
| Spanish22 | Low | 61 (30) | 49 | 10 | 20 | 34 | < .01 |
| Intermediate | 114 (56) | 88 | 4 | 10 | 22 | ||
| High | 29 (14) | 23 | 3 | 5 | 10 | ||
| Düsseldorf28 | Low | 15 (7) | 11 | 9 | 21 | 39 | < .01 |
| Intermediate | 119 (61) | 92 | 6 | 15 | 31 | ||
| High | 62 (32) | 50 | 3 | 7 | 12 | ||
| Lille12 | Low | 67 (34) | 53 | 9 | 19 | 34 | < .01 |
| Intermediate | 109 (56) | 83 | 4 | 9 | 20 | ||
| High | 20 (10) | 16 | 1 | 7 | 11 | ||
| IPSS6-15039 | Low | 18 (30) | 9 | 8 | 20 | 48 | .03 |
| Intermediate-1 | 27 (44) | 17 | 5 | 14 | 57 | ||
| Intermediate-2 | 11 (18) | 7 | 1 | 5 | 7 | ||
| High | 5 (8) | 5 | 1 | 6 | 8 | ||
| Scoring system . | Risk group . | No. of patients (%) . | No. of deaths . | Percentiles of survival (mo) . | P (log-rank test) . | ||
|---|---|---|---|---|---|---|---|
| 75% . | 50% . | 25% . | |||||
| Bournemouth14 | Low | 92 (45) | 74 | 8 | 18 | 33 | < .01 |
| Intermediate | 102 (50) | 77 | 4 | 8 | 18 | ||
| High | 10 (5) | 9 | 2 | 5 | 11 | ||
| Modified Bournemouth21 | Low | 72 (37) | 58 | 8 | 19 | 33 | .01 |
| High | 124 (63) | 96 | 4 | 8 | 19 | ||
| Spanish22 | Low | 61 (30) | 49 | 10 | 20 | 34 | < .01 |
| Intermediate | 114 (56) | 88 | 4 | 10 | 22 | ||
| High | 29 (14) | 23 | 3 | 5 | 10 | ||
| Düsseldorf28 | Low | 15 (7) | 11 | 9 | 21 | 39 | < .01 |
| Intermediate | 119 (61) | 92 | 6 | 15 | 31 | ||
| High | 62 (32) | 50 | 3 | 7 | 12 | ||
| Lille12 | Low | 67 (34) | 53 | 9 | 19 | 34 | < .01 |
| Intermediate | 109 (56) | 83 | 4 | 9 | 20 | ||
| High | 20 (10) | 16 | 1 | 7 | 11 | ||
| IPSS6-15039 | Low | 18 (30) | 9 | 8 | 20 | 48 | .03 |
| Intermediate-1 | 27 (44) | 17 | 5 | 14 | 57 | ||
| Intermediate-2 | 11 (18) | 7 | 1 | 5 | 7 | ||
| High | 5 (8) | 5 | 1 | 6 | 8 | ||
Applied only to patients with WBC counts ≤ 12 × 109/L.