Baseline laboratory values by subtype of von Willebrand disease
| VWD subtype . | Measurement . | |||
|---|---|---|---|---|
| VWF:Rcof, % median (range) . | FVIII:C, % median (range) . | VWF:Ag, % median (range) . | Bleeding time, min median (range) . | |
| Type 1 | 20 | 47 | 20 | 20 |
| (n = 15) | (6-80) | (14-145) | (0-68) | (3-30) |
| Type 2A | 19 | 56 | 49 | 26 |
| (n = 29) | (7-52) | (2-175) | (< 10-271) | (6-46) |
| Type 2B | 40 | 60 | 57 | > 30 |
| (n = 5) | (16-63) | (33-121) | (40-180) | (6-> 30) |
| Type 3 | < 10 | 6.0 | < 1 | > 30 |
| (n = 32) | (< 1-< 10) | (2-46) | (< 1-< 10) | (15-> 30) |
| Normal range | 56-150 | 54-158 | 52-160 | < 8-9.5 |
| VWD subtype . | Measurement . | |||
|---|---|---|---|---|
| VWF:Rcof, % median (range) . | FVIII:C, % median (range) . | VWF:Ag, % median (range) . | Bleeding time, min median (range) . | |
| Type 1 | 20 | 47 | 20 | 20 |
| (n = 15) | (6-80) | (14-145) | (0-68) | (3-30) |
| Type 2A | 19 | 56 | 49 | 26 |
| (n = 29) | (7-52) | (2-175) | (< 10-271) | (6-46) |
| Type 2B | 40 | 60 | 57 | > 30 |
| (n = 5) | (16-63) | (33-121) | (40-180) | (6-> 30) |
| Type 3 | < 10 | 6.0 | < 1 | > 30 |
| (n = 32) | (< 1-< 10) | (2-46) | (< 1-< 10) | (15-> 30) |
| Normal range | 56-150 | 54-158 | 52-160 | < 8-9.5 |
Value ranges of some measurements, particularly for patients with type 1 and type 2 VWD, include some values that are within the normal range for that measurement. They are likely to be explained by variation in results for patients who historically met criteria for VWD or by previous treatments not reported by the patient.