VWF multimer analyses
Samples . | Low–molecular-weight multimers, % . | High–molecular-weight multimers, % . |
---|---|---|
Normal plasma (control) | 46 | 54 |
Lot AP3034A | 54 | 46 |
Lot AP3034A + heat treatment | 60 | 40 |
Lot AP3020 | 61 | 39 |
Lot AP3020 + heat treatment | 65 | 36 |
Lot AP3018A | 63 | 37 |
Lot AP3018A + heat treatment | 63 | 37 |
Samples . | Low–molecular-weight multimers, % . | High–molecular-weight multimers, % . |
---|---|---|
Normal plasma (control) | 46 | 54 |
Lot AP3034A | 54 | 46 |
Lot AP3034A + heat treatment | 60 | 40 |
Lot AP3020 | 61 | 39 |
Lot AP3020 + heat treatment | 65 | 36 |
Lot AP3018A | 63 | 37 |
Lot AP3018A + heat treatment | 63 | 37 |
High–molecular-weight multimers were determined from densitometric scans and were defined as the area under the 5 molecular peaks from the high–molecular-weight end of the scan as described by Cumming et al.20