Steady-state hematology of STAT5ab−/−C57Bl/6 mice
| Hematologic parameter* . | STAT5ab+/+ . | STAT5ab−/− . | % Control . | P . |
|---|---|---|---|---|
| White blood cell/μL | 10 044 ± 1 975 | 4 540 ± 1 606 | 45 | < .005 |
| Absolute lymphocyte count/μL | 8 387 ± 1 656 | 1 087 ± 518 | 13 | < .005 |
| Absolute neutrophil count/μL | 1 163 ± 265 | 2 237 ± 841 | 192 | < .005 |
| Absolute monocyte count/μL | 495 ± 188 | 1 226 ± 874 | 248 | .09 |
| Hematocrit | 46 ± 3 | 35 ± 3 | 76 | < .01 |
| Hematologic parameter* . | STAT5ab+/+ . | STAT5ab−/− . | % Control . | P . |
|---|---|---|---|---|
| White blood cell/μL | 10 044 ± 1 975 | 4 540 ± 1 606 | 45 | < .005 |
| Absolute lymphocyte count/μL | 8 387 ± 1 656 | 1 087 ± 518 | 13 | < .005 |
| Absolute neutrophil count/μL | 1 163 ± 265 | 2 237 ± 841 | 192 | < .005 |
| Absolute monocyte count/μL | 495 ± 188 | 1 226 ± 874 | 248 | .09 |
| Hematocrit | 46 ± 3 | 35 ± 3 | 76 | < .01 |
STAT indicates signal transducers and activators of transcription.
Sample sizes consisted of 5 to 6 mice per group, analyzed between 4 and 6 weeks of age. Mice used for analysis appeared to be healthy and did not show signs of sickness related to splenomegaly disease. The % control is calculated for the average STAT5ab−/− relative to the STAT5ab+/+hematology values. P values were calculated by using the Student 2-tailed t test.