Table 2.

Absolute counts of lymphocytes and lymphocyte subsets in peripheral blood

GroupNormal C57BL/6 (n = 15)Syngeneic full-term fetal blood (n = 5)Allogeneic T-cell–depleted bone marrow (n = 4)Allogeneic full-term fetal blood (n = 8)
Total lymphocyte 4243 ± 892 15 400 ± 3745* 3051 ± 965 1534 ± 670*,, 
CD3+ 1363 ± 241 2682 ± 345* 1454 ± 516 931 ± 201*,, 
CD3+4+ 773 ± 147 1540 ± 167* 909 ± 274 605 ± 178*,, 
CD3+8+ 379 ± 69 1140 ± 198* 488 ± 254 305 ± 104 
CD4+CD62L+ 380 ± 57 433 ± 87 442 ± 132 146 ± 57*,, 
CD8+CD62L+ 187 ± 144 182 ± 113 112 ± 41 76 ± 56 
B220+ 2912 ± 714 14 424 ± 4657* 2352 ± 410 1024 ± 848*,, 
NK1.1+CD3 152 ± 44 164 ± 69 43 ± 10 56 ± 21*, 
GroupNormal C57BL/6 (n = 15)Syngeneic full-term fetal blood (n = 5)Allogeneic T-cell–depleted bone marrow (n = 4)Allogeneic full-term fetal blood (n = 8)
Total lymphocyte 4243 ± 892 15 400 ± 3745* 3051 ± 965 1534 ± 670*,, 
CD3+ 1363 ± 241 2682 ± 345* 1454 ± 516 931 ± 201*,, 
CD3+4+ 773 ± 147 1540 ± 167* 909 ± 274 605 ± 178*,, 
CD3+8+ 379 ± 69 1140 ± 198* 488 ± 254 305 ± 104 
CD4+CD62L+ 380 ± 57 433 ± 87 442 ± 132 146 ± 57*,, 
CD8+CD62L+ 187 ± 144 182 ± 113 112 ± 41 76 ± 56 
B220+ 2912 ± 714 14 424 ± 4657* 2352 ± 410 1024 ± 848*,, 
NK1.1+CD3 152 ± 44 164 ± 69 43 ± 10 56 ± 21*, 

Peripheral blood was obtained 200 days after transplantation and analyzed by flow cytometric analysis. The values represent absolute counts per μL blood (mean ± SD), which were obtained by using Flow-Count fluorospheres (Coulter, Miami, FL).

*

P < .05, compared with normal C57BL/6 mice.

P < .05, compared with syngeneic full-term fetal blood recipients (C57BL/6 → C57BL/6).

P < .05, compared with allogeneic T-cell–depleted bone marrow recipients.

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