Table 4.

Viable CD34+ cell recoveries after successive cell divisions in the presence or absence of growth factors or STI571

ConditionsRecovery in M1 (mean %)Recovery in M2 (mean %)Recovery in M3 (mean %)Recovery in M4 (mean %)Recovery in M5 (mean %)Total recovery (mean %)
 Total viable cells 
GFs 17 13 26 28 91 
GFs/STI571 16 15 23 1.6 0.9 56  
No GFs 14 21 10 1.4 — 47  
No GFs/STI571 11 0.2 — 22 
 Total viable CD34+ cells 
GFs 11 13 28 28 85 
GFs/STI571 15 16 23 1.6 0.9 55  
No GFs 13 25 11 1.4 — 51  
No GFs/STI571 11 10 0.2 — 24 
ConditionsRecovery in M1 (mean %)Recovery in M2 (mean %)Recovery in M3 (mean %)Recovery in M4 (mean %)Recovery in M5 (mean %)Total recovery (mean %)
 Total viable cells 
GFs 17 13 26 28 91 
GFs/STI571 16 15 23 1.6 0.9 56  
No GFs 14 21 10 1.4 — 47  
No GFs/STI571 11 0.2 — 22 
 Total viable CD34+ cells 
GFs 11 13 28 28 85 
GFs/STI571 15 16 23 1.6 0.9 55  
No GFs 13 25 11 1.4 — 51  
No GFs/STI571 11 10 0.2 — 24 

Numbers represent mean (n = 4) percentage recovery for the number of cells in each division peak, corrected for the number of divisions, as a fraction of input cell numbers (see “Materials and methods”).

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