Clinical features of AITL cases
| Case no. . | Age/sex . | Clinical features . | Site . | Initial diagnosis . |
|---|---|---|---|---|
| 1 | 65/M | Fever, generalized lymphadenopathy, hemolytic anemia | Lymph node | AITL |
| 2 | 62/M | Generalized lymphadenopathy | Lymph node | PTL |
| 3 | 59/M | Fever, cervical lymphadenopathy, abnormal liver function tests | Lymph node | AIL |
| 4 | 37/M | Generalized lymphadenopathy | Inguinal lymph node | Reactive |
| 5 | 82/M | Generalized lymphadenopathy, splenomegaly, positive Coombs test, night sweats | Lymph node | Reactive |
| 6 | 59/F | Cervical lymphadenopathy, pleural effusion | Lymph node | DLBL |
| 7 | 62/F | Lymphadenopathy, polyclonal gammopathy, hepatosplenomegaly | Lymph node | AIL |
| 8 | 70/M | Generalized lymphadenopathy, weight loss, rash | Axillary lymph node | HL, TRBL |
| 9 | 48/M | Not available | Lymph node | AITL |
| 10 | 64/F | Generalized lymphadenopathy, fever, pruritus, night sweats | Axillary lymph node | AIL?, reactive? |
| 11 | 76/F | Generalized lymphadenopathy, hepatosplenomegaly | Lymph node | AIL?, CD?, reactive? |
| 12 | 79/F | Not available | Lymph node | AITL?, PTL? |
| 13 | 84/F | Lymphadenopathy, rash | Inguinal lymph node | PTL?, TRBL? |
| 14 | 78/M | Fever, generalized lymphadenopathy, splenomegaly, skin rash | Lymph node | NHL |
| 15A | 42/M | Generalized lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, weight loss | Lymph node February 1998 | Reactive?, CD? |
| 15B | Lymph node March 2000 | |||
| 16A | 60/F | Fever, bilateral inguinal lymphadenopathy, splenomegaly | Inguinal lymph node 2000 | NHL |
| 16B | Lymph node 2001 | DLBL | ||
| 17 | 58/F | Generalized lymphadenopathy, “B” symptoms | Lymph node | DLBL |
| 18 | 78/M | Generalized lymphadenopathy, positive Coombs test, hemolytic anemia, hypergammaglobulinemia, | Cervical lymph node | AIL |
| 19 | 55/M | Generalized lymphadenopathy, fever, weight loss | Inguinal lymph node 2000 | Reactive |
| 20 | 71/M | Inguinal lymphadenopathy, weight loss | Inguinal lymph node | DLBL |
| 21 | 39/F | Generalized lymphadenopathy, night sweats | Lymph node | AITL |
| 22 | 77/F | Generalized lymphadenopathy, splenomegaly, “B” symptoms | Axillary lymph node | PTL?, HL? |
| 23 | 52/F | Lymphadenopathy, high ESR | Cervical lymph node | DLBL?, HL? |
| 24 | 61/M | Axillary, inguinal lymphadenopathy, hepatomegaly, pneumonia | Axillary lymph node | AIL |
| 25 | 61/M | Not available | Lymph node | AITL |
| 26 | 74/F | Generalized lymphadenopathy, pruritus | Cervical lymph node | AIL |
| 27 | 78/F | Lymphadenopathy, “B” symptoms | Inguinal lymph node | TRBL |
| 28 | 78/M | Generalized lymphadenopathy, rash, weight loss | Inguinal lymph node | TRBL?, PTL? |
| 29 | 52/M | Generalized lymphadenopathy, hepatosplenomegaly, anemia | Lymph node | FDC tumor |
| 30 | 59/M | Generalized lymphadenopathy | Lymph node | AIL |
| Case no. . | Age/sex . | Clinical features . | Site . | Initial diagnosis . |
|---|---|---|---|---|
| 1 | 65/M | Fever, generalized lymphadenopathy, hemolytic anemia | Lymph node | AITL |
| 2 | 62/M | Generalized lymphadenopathy | Lymph node | PTL |
| 3 | 59/M | Fever, cervical lymphadenopathy, abnormal liver function tests | Lymph node | AIL |
| 4 | 37/M | Generalized lymphadenopathy | Inguinal lymph node | Reactive |
| 5 | 82/M | Generalized lymphadenopathy, splenomegaly, positive Coombs test, night sweats | Lymph node | Reactive |
| 6 | 59/F | Cervical lymphadenopathy, pleural effusion | Lymph node | DLBL |
| 7 | 62/F | Lymphadenopathy, polyclonal gammopathy, hepatosplenomegaly | Lymph node | AIL |
| 8 | 70/M | Generalized lymphadenopathy, weight loss, rash | Axillary lymph node | HL, TRBL |
| 9 | 48/M | Not available | Lymph node | AITL |
| 10 | 64/F | Generalized lymphadenopathy, fever, pruritus, night sweats | Axillary lymph node | AIL?, reactive? |
| 11 | 76/F | Generalized lymphadenopathy, hepatosplenomegaly | Lymph node | AIL?, CD?, reactive? |
| 12 | 79/F | Not available | Lymph node | AITL?, PTL? |
| 13 | 84/F | Lymphadenopathy, rash | Inguinal lymph node | PTL?, TRBL? |
| 14 | 78/M | Fever, generalized lymphadenopathy, splenomegaly, skin rash | Lymph node | NHL |
| 15A | 42/M | Generalized lymphadenopathy, fever, hepatosplenomegaly, hemolytic anemia, weight loss | Lymph node February 1998 | Reactive?, CD? |
| 15B | Lymph node March 2000 | |||
| 16A | 60/F | Fever, bilateral inguinal lymphadenopathy, splenomegaly | Inguinal lymph node 2000 | NHL |
| 16B | Lymph node 2001 | DLBL | ||
| 17 | 58/F | Generalized lymphadenopathy, “B” symptoms | Lymph node | DLBL |
| 18 | 78/M | Generalized lymphadenopathy, positive Coombs test, hemolytic anemia, hypergammaglobulinemia, | Cervical lymph node | AIL |
| 19 | 55/M | Generalized lymphadenopathy, fever, weight loss | Inguinal lymph node 2000 | Reactive |
| 20 | 71/M | Inguinal lymphadenopathy, weight loss | Inguinal lymph node | DLBL |
| 21 | 39/F | Generalized lymphadenopathy, night sweats | Lymph node | AITL |
| 22 | 77/F | Generalized lymphadenopathy, splenomegaly, “B” symptoms | Axillary lymph node | PTL?, HL? |
| 23 | 52/F | Lymphadenopathy, high ESR | Cervical lymph node | DLBL?, HL? |
| 24 | 61/M | Axillary, inguinal lymphadenopathy, hepatomegaly, pneumonia | Axillary lymph node | AIL |
| 25 | 61/M | Not available | Lymph node | AITL |
| 26 | 74/F | Generalized lymphadenopathy, pruritus | Cervical lymph node | AIL |
| 27 | 78/F | Lymphadenopathy, “B” symptoms | Inguinal lymph node | TRBL |
| 28 | 78/M | Generalized lymphadenopathy, rash, weight loss | Inguinal lymph node | TRBL?, PTL? |
| 29 | 52/M | Generalized lymphadenopathy, hepatosplenomegaly, anemia | Lymph node | FDC tumor |
| 30 | 59/M | Generalized lymphadenopathy | Lymph node | AIL |
AITL indicates angioimmunoblastic T-cell lymphoma; PTL, peripheral T-cell lymphoma; AIL, angioimmunoblastic lymphadenopathy; DLBL, diffuse large B-cell lymphoma; HL, Hodgkin lymphoma; TRBL, T-cell–rich B-cell lymphoma; NHL, non-Hodgkin lymphoma; CD, Castleman disease; FDC, follicular dendritic cell.