Effect of rh TIMP-1 and TIMP-1 antibody (Ab; clone 7-6C1) on tritium-thymidine uptake in cell lines derived from Hodgkin/Reed-Sternberg cells
| Cell line . | Control . | rhTIMP-1 . | TIMP-1 Ab . |
|---|---|---|---|
| KMH2 | 1674 ± 254 | 1620 ± 581 | 1710 ± 240 |
| L591 | 138 ± 56 | 115 ± 20 | 133 ± 21 |
| Holden | 4844 ± 487 | 4478 ± 287 | 4280 ± 207 |
| Sup-HD | 7481 ± 812 | 7144 ± 619 | 7686 ± 566 |
| Cell line . | Control . | rhTIMP-1 . | TIMP-1 Ab . |
|---|---|---|---|
| KMH2 | 1674 ± 254 | 1620 ± 581 | 1710 ± 240 |
| L591 | 138 ± 56 | 115 ± 20 | 133 ± 21 |
| Holden | 4844 ± 487 | 4478 ± 287 | 4280 ± 207 |
| Sup-HD | 7481 ± 812 | 7144 ± 619 | 7686 ± 566 |
Values are mean ± SD counts per minute derived from 6-fold cultures. There were no significant differences between values for controls and values for either rhTIMP-1 (500 ng/mL) or TIMP-1 Ab (5 μg/mL).