Table 4.

Tissue F4/80+ cell densities

TissueAge of miceWild typeCsf1op/Csf1opCsf1r/Csf1r
Bone marrow4-150,4-151 2 wk 697.7 ± 11.7 210.5 ± 14.8 173.7 ± 41.0 
Liver4-150,4-151 2 d 678.1 ± 108.4 413.4 ± 13.0 463.7 ± 45.3 
Liver4-150,4-151 4 mo 372.9 ± 44.2 124.3 ± 7.2 150.0 ± 68.2 
Kidney4-150,4-151, 2 wk 184.3 ± 83.0 34.5 ± 1.6 12.3 ± 0.4 
Thymus4-150,4-151 2 wk 376.4 ± 40.1 110.6 ± 18.1 168.3 ± 15.2 
Langerhans cells4-150,4-151 2 d 15.8 ± 1.34-153 3.0 ± 1.44-153 2.0 ± 1.44-153 
Dermis4-150,4-151 2 d 253.1 ± 56.0 15.4 ± 5.1 32.5 ± 10.0 
Testes4-150,4-151 2 wk 178.3 ± 83.2 46.7 ± 22.2 34.6 ± 19.4 
TissueAge of miceWild typeCsf1op/Csf1opCsf1r/Csf1r
Bone marrow4-150,4-151 2 wk 697.7 ± 11.7 210.5 ± 14.8 173.7 ± 41.0 
Liver4-150,4-151 2 d 678.1 ± 108.4 413.4 ± 13.0 463.7 ± 45.3 
Liver4-150,4-151 4 mo 372.9 ± 44.2 124.3 ± 7.2 150.0 ± 68.2 
Kidney4-150,4-151, 2 wk 184.3 ± 83.0 34.5 ± 1.6 12.3 ± 0.4 
Thymus4-150,4-151 2 wk 376.4 ± 40.1 110.6 ± 18.1 168.3 ± 15.2 
Langerhans cells4-150,4-151 2 d 15.8 ± 1.34-153 3.0 ± 1.44-153 2.0 ± 1.44-153 
Dermis4-150,4-151 2 d 253.1 ± 56.0 15.4 ± 5.1 32.5 ± 10.0 
Testes4-150,4-151 2 wk 178.3 ± 83.2 46.7 ± 22.2 34.6 ± 19.4 

Densities in cells/mm2 average of multiple counts (±SD, n = 4) of tissue sections from at least 2 mice per genotype.

F4-150

Significant differences between wild type andCsf1op/Csf1op (P ≤ .05).

F4-151

Significant differences between wild type andCsf1r/Csf1r (P≤ .05).

Significant differences betweenCsf1op/Csf1op andCsf1r/Csf1r (P≤ .05).

F4-153

Densities in cells/mm average of multiple counts (±SD, n = 4) of tissue sections from at least 2 mice per genotype.

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