Table 1. Frequency of genotypes of... | American Society of Hematology

Table 1.

Frequency of genotypes of progeny of single heterozygote crosses of Csf1^op andCsf1r⁻ mutations

Age of progeny	Cross	Total progeny	Homozygous wild type	Heterozygotes	Homozygous mutant	χ² test probability^*
1 d	Csf1⁺/Csf1^op × Csf1⁺/Csf1^op	40	12 (1.2)^†	17 (1.7)	11 (1.1)	0.62
	Csf1r⁺/Csf1r⁻ × Csf1r⁺/Csf1r⁻	72	21 (1.17)	38 (2.11)	13 (0.72)	0.37
3 wk	Csf1⁺/Csf1^op × Csf1⁺/Csf1^op	214	71 (1.32)	109 (2.04)	34 (0.64)	0.002
	Csf1r⁺/Csf1r⁻ × Csf1r⁺/Csf1r⁻	393	107 (1.09)	221 (2.24)	65 (0.66)	0.005

Age of progeny	Cross	Total progeny	Homozygous wild type	Heterozygotes	Homozygous mutant	χ² test probability^*
1 d	Csf1⁺/Csf1^op × Csf1⁺/Csf1^op	40	12 (1.2)^†	17 (1.7)	11 (1.1)	0.62
	Csf1r⁺/Csf1r⁻ × Csf1r⁺/Csf1r⁻	72	21 (1.17)	38 (2.11)	13 (0.72)	0.37
3 wk	Csf1⁺/Csf1^op × Csf1⁺/Csf1^op	214	71 (1.32)	109 (2.04)	34 (0.64)	0.002
	Csf1r⁺/Csf1r⁻ × Csf1r⁺/Csf1r⁻	393	107 (1.09)	221 (2.24)	65 (0.66)	0.005

Probability that results do not differ significantly from the 1:2:1 ratio.

Ratio compared with expected 1:2:1 ratio of an independently segregating gene.