Table 2.

Effect of various agonists on CXCR4 expression in L540 cells

No variation  
 Medium * 
 BerH2 * 
 Anti-CD34 * 
 GM-CSF * 
 IL-2 * 
 Cycloheximide * 
Down-regulation  
 PMA + ionomycin −−  
 IFN-γ −  
 IL-4 −  
 IL-6 − 
Up-regulation  
 IL-10 +  
 M44 ++ 
 M67 ++  
 M44/M67 + cycloheximide +++ 
No variation  
 Medium * 
 BerH2 * 
 Anti-CD34 * 
 GM-CSF * 
 IL-2 * 
 Cycloheximide * 
Down-regulation  
 PMA + ionomycin −−  
 IFN-γ −  
 IL-4 −  
 IL-6 − 
Up-regulation  
 IL-10 +  
 M44 ++ 
 M67 ++  
 M44/M67 + cycloheximide +++ 

See “Materials and methods” for concentrations.

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