Table 1.

Expression of CD2 in bone marrow MCs

DiagnosisSurface CD2CD2 immunohistochemistry
SM +  
SM 
SM nt  
SM nt  
SM nt  
SM 
SM nt  
SM nt  
SM +  
SM nt 
SM +  
SM +  
SM 
MDS/RA − nt  
MDS/RA − nt  
MDS/RARS − nt 
MDS/RAEB nt −  
MDS/RAEB nt − 
MDS/RAEB-T − nt  
MDS/RAEB-T − nt 
MDS/RAEB-T − nt  
Reactive BM − nt  
Reactive BM nt −  
Reactive BM nt −  
Reactive BM − − 
Normal BM − nt 
DiagnosisSurface CD2CD2 immunohistochemistry
SM +  
SM 
SM nt  
SM nt  
SM nt  
SM 
SM nt  
SM nt  
SM +  
SM nt 
SM +  
SM +  
SM 
MDS/RA − nt  
MDS/RA − nt  
MDS/RARS − nt 
MDS/RAEB nt −  
MDS/RAEB nt − 
MDS/RAEB-T − nt  
MDS/RAEB-T − nt 
MDS/RAEB-T − nt  
Reactive BM − nt  
Reactive BM nt −  
Reactive BM nt −  
Reactive BM − − 
Normal BM − nt 

Surface CD2 expression on BM MCs was determined by multicolor flow cytometry using mAb S5.2. CD2 expression in MCs was also analyzed by immunohistochemistry in serial BM sections stained with mAb G3 (tryptase) and mAb AB75 (CD2).

+ indicates > 90% of cells reactive; −, < 10% of cells reactive; and nt, not tested.

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