Table 1.

Genes down-regulated by Erg GeneBloc treatment

GenesFunctional category
ICAM-2 Cell adhesion 
RhoA Cytoskeleton/signaling  
SPARC Cell adhesion/extracellular matrix  
TSP-1 Cell adhesion/extracellular matrix  
vWF Cell adhesion/hemostasis 
GenesFunctional category
ICAM-2 Cell adhesion 
RhoA Cytoskeleton/signaling  
SPARC Cell adhesion/extracellular matrix  
TSP-1 Cell adhesion/extracellular matrix  
vWF Cell adhesion/hemostasis 

RNA was prepared from HUVECs treated with 50 nM Erg GeneBloc (GB566) or a control GeneBloc (GBC3.3) was used to prepare cDNA probes for DGE analysis. Genes that were consistently down-regulated at 24, 48, and 72 hours are listed.

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