Table 5.

Response to therapy and HLA phenotype

ComparisonHLA-AHLA-BHLA-CwHLA-DRHLA-DQ
Immunosuppression
vs controls 
NS B14
13% vs 8%
z = 3.4
N = 305 
NS DR2
42% vs 28%
z = 5.3
N = 281 
NS 
ComparisonHLA-AHLA-BHLA-CwHLA-DRHLA-DQ
Immunosuppression
vs controls 
NS B14
13% vs 8%
z = 3.4
N = 305 
NS DR2
42% vs 28%
z = 5.3
N = 281 
NS 

HLA phenotype was analyzed in patients with bone marrow failure treated with immunosuppressive therapy (as indicated in “Patients, materials, and methods”) and compared to the controls. Only alleles that are substantially different from controls are shown.

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