Oxygenated PFE, but not deoxygenated PFE, ameliorates increased PRU caused by SS RBC in PAF-treated ex vivo mesocecum vasculature
| Infusion sequence . | PRU . | Mean ± SD . | ||
|---|---|---|---|---|
| 1 . | 2 . | 3 . | ||
| Pre-SS infusion | 6.9 | 6.2 | 7.2 | 6.8 ± 0.5 |
| Post-SS infusion | 8.6 | 10.1 | 11.6 | 10.1 ± 1.53-150 |
| Deoxy PFE | 7.9 | 9.4 | 9.6 | 9.0 ± 0.93-150 |
| Oxy PFE | 6.8 | 6.5 | 7.5 | 6.9 ± 0.5 |
| Infusion sequence . | PRU . | Mean ± SD . | ||
|---|---|---|---|---|
| 1 . | 2 . | 3 . | ||
| Pre-SS infusion | 6.9 | 6.2 | 7.2 | 6.8 ± 0.5 |
| Post-SS infusion | 8.6 | 10.1 | 11.6 | 10.1 ± 1.53-150 |
| Deoxy PFE | 7.9 | 9.4 | 9.6 | 9.0 ± 0.93-150 |
| Oxy PFE | 6.8 | 6.5 | 7.5 | 6.9 ± 0.5 |
PRU = Pa-Pv (mm Hg)/venous outflow (mL/min)/tissue weight (g).
Abbreviations are explained in Table 1.
Three mesocecum preparations were used (1 to 3).
P < .05 compared with pre-SS and PFE (Newman-Keuls multiple comparisons).