PFE ameliorates increased PRU caused by SS RBCs in ex vivo mesocecum vasculature
| Infusion sequence . | PRU . | Mean ± SD . | ||||||
|---|---|---|---|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | 5 . | 6 . | 7 . | ||
| Pre-SS infusion | 4.5 | 5.3 | 5.6 | 4.6 | 5.2 | 4.3 | 5.4 | 5.0 ± 0.5 |
| Post-SS infusion | 6.9 | 8.5 | 7.6 | 6.3 | 6.5 | 8.4 | 8.1 | 7.5 ± 0.9* |
| Oxy Ringer | — | — | — | — | 6.5 | 7.7 | 7.6 | 7.3 ± 0.7* |
| Oxy PFE | 5.1 | 5.7 | 5.9 | 4.7 | 6.1 | 5.2 | 6.7 | 5.6 ± 0.7 |
| Infusion sequence . | PRU . | Mean ± SD . | ||||||
|---|---|---|---|---|---|---|---|---|
| 1 . | 2 . | 3 . | 4 . | 5 . | 6 . | 7 . | ||
| Pre-SS infusion | 4.5 | 5.3 | 5.6 | 4.6 | 5.2 | 4.3 | 5.4 | 5.0 ± 0.5 |
| Post-SS infusion | 6.9 | 8.5 | 7.6 | 6.3 | 6.5 | 8.4 | 8.1 | 7.5 ± 0.9* |
| Oxy Ringer | — | — | — | — | 6.5 | 7.7 | 7.6 | 7.3 ± 0.7* |
| Oxy PFE | 5.1 | 5.7 | 5.9 | 4.7 | 6.1 | 5.2 | 6.7 | 5.6 ± 0.7 |
PRU = Pa-Pv (mm Hg)/venous outflow (mL/min)/tissue weight (g).
Pa indicates arterial perfusion pressure; Pv, venous outflow pressure.
Seven mesocecum preparations were used (1 to 7).
P < .05 compared with pre-SS and PFE (Newman-Keuls multiple comparisons).