Table 1.

Clinical characteristics of 109 patients randomized in the 2 trials

Trial 1Trial 2
No ATGATG 7.5 (mg/kg)PNo ATGATG 15 (mg/kg)P
No. of patients 25 29  28 27  
Donor age (y) 38 35 .2 37 36 .7 
 CMV+ 48% 55% .6 46% 51% .9 
Recipient age (y) 29 28 .7 28 32 .2 
 (range) (13-51) (18-48)  (14-46) (14-52)  
 CMV+ 72% 79% .5 62% 74% .2 
Interval Dx-BMT (d) 713 871 .03 547 608 .7 
Disease 1st CR/CP 60% 62% .8 36% 22% .2 
Number cells × 108/kg 3.4 .2 3.6 3.3 .3 
 (range) (1.2-7.8) (1.4-13)  (1.6-7.6) (0.8-6.5)  
Trial 1Trial 2
No ATGATG 7.5 (mg/kg)PNo ATGATG 15 (mg/kg)P
No. of patients 25 29  28 27  
Donor age (y) 38 35 .2 37 36 .7 
 CMV+ 48% 55% .6 46% 51% .9 
Recipient age (y) 29 28 .7 28 32 .2 
 (range) (13-51) (18-48)  (14-46) (14-52)  
 CMV+ 72% 79% .5 62% 74% .2 
Interval Dx-BMT (d) 713 871 .03 547 608 .7 
Disease 1st CR/CP 60% 62% .8 36% 22% .2 
Number cells × 108/kg 3.4 .2 3.6 3.3 .3 
 (range) (1.2-7.8) (1.4-13)  (1.6-7.6) (0.8-6.5)  

Dx-BMT, interval diagnosis transplant; 1st CR/CP, first remission or chronic phase.

P < .05.

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