Mobilization and collection of peripheral blood stem cells
| Subject . | Initial WBC . | Maximal WBC . | Initial CD34+/μL . | Maximal CD34+/μL . | Total days G-CSF . | Days of apheresis . | Blood volumes . | Liters processed . | Nucleated cells . | Total CD34+ . | Actual CD34+/kg . | Target CD34+/kg . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 3.6 | 8.3 | 3.2 | 3.6 | 10 | — | — | — | — | — | — | — |
| 2 | 2.9 | 8.4 | 2.3 | 5.7 | 14 | — | — | — | — | — | — | — |
| 3 | 5 | 19.4 | 3.5 | 7.8 | 12 | 7 | 40 | 60 | 14.2 × 1010 | 8.5 × 107 | 4.4 × 106 | 2.0 × 106 |
| 4 | 2.4 | 10.7 | 1.4 | 8.8 | 21 | 8 | 47 | 93 | 7.9 × 1010 | 6.7 × 107 | 2.7 × 106 | 1.5 × 106 |
| 5 | 11.2 | 20.4 | 10.3 | 15.0 | 18 | 2 | 11 | 41 | 10.0 × 1010 | 9.2 × 107 | 2.0 × 106 | 1.2 × 106 |
| 6 | 3.9 | 29.5 | 4.7 | 17.7 | 6 | 2 | 12 | 56 | 18.7 × 1010 | 13.7 × 107 | 2.4 × 106 | 2.3 × 106 |
| 7 | 3.4 | 7.0 | 6.5 | 8.8 | 14 | 3 | 18 | 96 | 12.0 × 1010 | 13.9 × 107 | 2.0 × 106 | 2.0 × 106 |
| 8 | 2.7 | 12.1 | 1.9 | 18.7 | 13 | 3 | 12 | 68 | 8.6 × 1010 | 16.0 × 107 | 2.3 × 106 | 2.2 × 106 |
| Mean | 4.4 | 14.5 | 4.2 | 10.8 | 14 | 4 | 23 | 69 | 11.9 × 1010 | 11.3 × 107 | 2.6 × 106 | 1.9 × 106 |
| Subject . | Initial WBC . | Maximal WBC . | Initial CD34+/μL . | Maximal CD34+/μL . | Total days G-CSF . | Days of apheresis . | Blood volumes . | Liters processed . | Nucleated cells . | Total CD34+ . | Actual CD34+/kg . | Target CD34+/kg . |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 3.6 | 8.3 | 3.2 | 3.6 | 10 | — | — | — | — | — | — | — |
| 2 | 2.9 | 8.4 | 2.3 | 5.7 | 14 | — | — | — | — | — | — | — |
| 3 | 5 | 19.4 | 3.5 | 7.8 | 12 | 7 | 40 | 60 | 14.2 × 1010 | 8.5 × 107 | 4.4 × 106 | 2.0 × 106 |
| 4 | 2.4 | 10.7 | 1.4 | 8.8 | 21 | 8 | 47 | 93 | 7.9 × 1010 | 6.7 × 107 | 2.7 × 106 | 1.5 × 106 |
| 5 | 11.2 | 20.4 | 10.3 | 15.0 | 18 | 2 | 11 | 41 | 10.0 × 1010 | 9.2 × 107 | 2.0 × 106 | 1.2 × 106 |
| 6 | 3.9 | 29.5 | 4.7 | 17.7 | 6 | 2 | 12 | 56 | 18.7 × 1010 | 13.7 × 107 | 2.4 × 106 | 2.3 × 106 |
| 7 | 3.4 | 7.0 | 6.5 | 8.8 | 14 | 3 | 18 | 96 | 12.0 × 1010 | 13.9 × 107 | 2.0 × 106 | 2.0 × 106 |
| 8 | 2.7 | 12.1 | 1.9 | 18.7 | 13 | 3 | 12 | 68 | 8.6 × 1010 | 16.0 × 107 | 2.3 × 106 | 2.2 × 106 |
| Mean | 4.4 | 14.5 | 4.2 | 10.8 | 14 | 4 | 23 | 69 | 11.9 × 1010 | 11.3 × 107 | 2.6 × 106 | 1.9 × 106 |
WBC × 109/L; G-CSF administered as 10 μg/kg per day; total blood volumes and liters of blood processed during apheresis; number of CD34+ cells collected relative to actual and target weight; target weight based on fifth-percentile weight 5 years in the future.