Data on patients who died
| Case no. . | Gender . | Age at death (y) . | Cause of death . | Months in IFN-α . | Months off IFN-α . | Cause of IFN-α discontinuation . | Last cytogenetics before death . |
|---|---|---|---|---|---|---|---|
| 185 | M | 46 | Liver failure | 21 | Less than 1 | Liver failure | PCgR |
| 515 | M | 60 | Dementia | (∼ 30) | (At most 12) | Dementia | CCgR |
| 411 | F | 63 | Cardiac arrest | 86 | 6 | Liver toxicity | CCgR |
| 123 | M | 66 | Myocardial infarction | 42 | — | (death) | CCgR |
| 495 | M | 67 | Not identified, sudden death at home | 56 | — | (death) | CCgR |
| 238 | M | 69 | Bronchogenic carcinoma | 71 | 4 | Cancer | PCgR |
| 237 | M | 71 | Pulmonary thromboembolism | 88 | 3 | Not identified | Less than PCgR |
| 253 | M | 73 | Myocardial infarction | 70 | 19 | Loss of compliance | CCgR |
| 519 | M | 76 | Ictus cerebri | 34 | 25 | Loss of compliance | Less than PGgR |
| Case no. . | Gender . | Age at death (y) . | Cause of death . | Months in IFN-α . | Months off IFN-α . | Cause of IFN-α discontinuation . | Last cytogenetics before death . |
|---|---|---|---|---|---|---|---|
| 185 | M | 46 | Liver failure | 21 | Less than 1 | Liver failure | PCgR |
| 515 | M | 60 | Dementia | (∼ 30) | (At most 12) | Dementia | CCgR |
| 411 | F | 63 | Cardiac arrest | 86 | 6 | Liver toxicity | CCgR |
| 123 | M | 66 | Myocardial infarction | 42 | — | (death) | CCgR |
| 495 | M | 67 | Not identified, sudden death at home | 56 | — | (death) | CCgR |
| 238 | M | 69 | Bronchogenic carcinoma | 71 | 4 | Cancer | PCgR |
| 237 | M | 71 | Pulmonary thromboembolism | 88 | 3 | Not identified | Less than PCgR |
| 253 | M | 73 | Myocardial infarction | 70 | 19 | Loss of compliance | CCgR |
| 519 | M | 76 | Ictus cerebri | 34 | 25 | Loss of compliance | Less than PGgR |
Nine patients died in chronic phase; they are listed by age. In case no. 185 liver failure was attributed to acute paracetamol toxicity. In case no. 515 the exact duration of IFN-α treatment could not be retrieved, but was estimated to be about 30 months. In addition to these 9 patients, 2 patients died because of BMT, one allogeneic and one autologous. Both were submitted to BMT in CCgR.