Table 5. Incidence of acute and chronic... | American Society of Hematology

Table 5.

Incidence of acute and chronic GVHD after allogeneic PBSC or BM transplantation

Study	Acute GVHD grades II-IV (grades III-IV) (100-d probability)		Chronic GVHD
Study	BM (%)	PBSC (%)	BM (%)	PBSC (%)
Vigorito et al³⁸	19	27	53 overall	71 overall
			50 limited^5-150	0 limited^5-150
			50 extensive^5-150	100 extensive^5-150
			(median FU, 631 d)	(median FU, 335 d)
Blaise et al³⁹	42	44	30 overall^5-150	54.5 overall^5-150
			73 limited^5-150	37.5 limited^5-150
			27 extensive^5-150	62.5 extensive^5-150
			(median FU, 20 mo)	(median FU, 20 mo)
Ringden et al⁴⁰	20	30	85 overall	59 overall
			83 limited	82 limited
			17 extensive	12 extensive
			(median FU, 16 mo)	(median FU, 10 mo)
Heldal et al⁴¹	10	21	27	56
			75 limited	73 limited
			25 extensive	27 extensive
			(median FU, 27 mo)	(median FU, 27 mo)
Powles et al⁴²	47	50	40 (2-y probability)	44 (2-y probability)
Schmitz et al⁴³	39^5-150	52^5-150	53^5-150(at 2 y)	74^5-150 (at 2 y)
	(16)^5-150	(28)^5-150
Simpson et al⁴⁴	40	40	39 (at 6 mo)	47 (at 6 mo)
			55 (at 1 y)	71 (at 1 y)
Champlin et al⁴⁵	35 (19)	40 (13)	53^5-150	65^5-150
			51 limited^5-150	49 limited^5-150
			49 extensive^5-150	51 extensive^5-150
			(1-y probability)	(1-y probability)
Bensinger et al¹⁰	57 (12)	64 (15)	28	38
			(median FU, 20 mo)	(median FU, 20 mo)

Study	Acute GVHD grades II-IV (grades III-IV) (100-d probability)		Chronic GVHD
Study	BM (%)	PBSC (%)	BM (%)	PBSC (%)
Vigorito et al³⁸	19	27	53 overall	71 overall
			50 limited^5-150	0 limited^5-150
			50 extensive^5-150	100 extensive^5-150
			(median FU, 631 d)	(median FU, 335 d)
Blaise et al³⁹	42	44	30 overall^5-150	54.5 overall^5-150
			73 limited^5-150	37.5 limited^5-150
			27 extensive^5-150	62.5 extensive^5-150
			(median FU, 20 mo)	(median FU, 20 mo)
Ringden et al⁴⁰	20	30	85 overall	59 overall
			83 limited	82 limited
			17 extensive	12 extensive
			(median FU, 16 mo)	(median FU, 10 mo)
Heldal et al⁴¹	10	21	27	56
			75 limited	73 limited
			25 extensive	27 extensive
			(median FU, 27 mo)	(median FU, 27 mo)
Powles et al⁴²	47	50	40 (2-y probability)	44 (2-y probability)
Schmitz et al⁴³	39^5-150	52^5-150	53^5-150(at 2 y)	74^5-150 (at 2 y)
	(16)^5-150	(28)^5-150
Simpson et al⁴⁴	40	40	39 (at 6 mo)	47 (at 6 mo)
			55 (at 1 y)	71 (at 1 y)
Champlin et al⁴⁵	35 (19)	40 (13)	53^5-150	65^5-150
			51 limited^5-150	49 limited^5-150
			49 extensive^5-150	51 extensive^5-150
			(1-y probability)	(1-y probability)
Bensinger et al¹⁰	57 (12)	64 (15)	28	38
			(median FU, 20 mo)	(median FU, 20 mo)

NA indicates not available; FU, follow-up.

Statistical significance.