hCD4 reporter gene expression on peritoneal macrophages and T cells from lymph nodes of hCD4 Tg mice
| Construct . | Founder . | hCD4 expression on specific populations (%) . | |||
|---|---|---|---|---|---|
| Peritoneal macrophages . | Lymph node . | ||||
| Mac1+ . | Class II+ . | CD4 SP . | CD8 SP . | ||
| CD4A/CD4 | 5 566 | 96.4 ± 0.8 | 97.1 ± 1.1 | 87.0 ± 3.3 | 3.4 ± 2.6 |
| 8 277 | 92.2 ± 3.5 | 92.3 ± 0.7 | 45.6 ± 3.8 | 4.3 ± 1.5 | |
| CD4C/CD4 | 8 951 | 92.8 ± 3.6 | 94.4 ± 1.8 | 81.0 ± 11.2 | 13.9 ± 2.0 |
| 8 956 | 92.5 ± 6.0 | 90.0 ± 3.6 | 94.2 ± 1.8 | 24.1 ± 11.2 | |
| CD4E/CD4 | 19 762 | 2.3 ± 1.8 | 2.3 ± 2.1 | ND | 11.2 ± 2.3 |
| 21 428 | 1.3 ± 1.4 | 1.9 ± 1.6 | 92.1 ± 6.7 | 18.0 ± 8.6 | |
| 21 429 | 2.8 ± 2.1 | 3.1 ± 2.8 | 39.7 ± 12.5 | 6.0 ± 2.1 | |
| CD4F/CD4 | 19 468 | 0.6 ± 0.6 | 0.5 ± 0.6 | ND | 4.0 ± 0.4 |
| 19 508 | 1.2 ± 1.6 | 3.2 ± 4.5 | 89.0 ± 9.6 | 3.34 ± 0.2 | |
| 19 523 | 0.8 ± 0.2 | 2.7 ± 1.4 | 50.9 ± 16.3 | 2.6 ± 1.0 | |
| CD4H/CD4 | 26 655 | 99.3 ± 1.2 | 97.9 ± 2.2 | 83.6 ± 2.7 | 5.4 ± 4.0 |
| 26 710 | 92.9 ± 5.1 | 89.8 ± 7.7 | 87.7 ± 1.6 | 14.8 ± 7.6 | |
| Construct . | Founder . | hCD4 expression on specific populations (%) . | |||
|---|---|---|---|---|---|
| Peritoneal macrophages . | Lymph node . | ||||
| Mac1+ . | Class II+ . | CD4 SP . | CD8 SP . | ||
| CD4A/CD4 | 5 566 | 96.4 ± 0.8 | 97.1 ± 1.1 | 87.0 ± 3.3 | 3.4 ± 2.6 |
| 8 277 | 92.2 ± 3.5 | 92.3 ± 0.7 | 45.6 ± 3.8 | 4.3 ± 1.5 | |
| CD4C/CD4 | 8 951 | 92.8 ± 3.6 | 94.4 ± 1.8 | 81.0 ± 11.2 | 13.9 ± 2.0 |
| 8 956 | 92.5 ± 6.0 | 90.0 ± 3.6 | 94.2 ± 1.8 | 24.1 ± 11.2 | |
| CD4E/CD4 | 19 762 | 2.3 ± 1.8 | 2.3 ± 2.1 | ND | 11.2 ± 2.3 |
| 21 428 | 1.3 ± 1.4 | 1.9 ± 1.6 | 92.1 ± 6.7 | 18.0 ± 8.6 | |
| 21 429 | 2.8 ± 2.1 | 3.1 ± 2.8 | 39.7 ± 12.5 | 6.0 ± 2.1 | |
| CD4F/CD4 | 19 468 | 0.6 ± 0.6 | 0.5 ± 0.6 | ND | 4.0 ± 0.4 |
| 19 508 | 1.2 ± 1.6 | 3.2 ± 4.5 | 89.0 ± 9.6 | 3.34 ± 0.2 | |
| 19 523 | 0.8 ± 0.2 | 2.7 ± 1.4 | 50.9 ± 16.3 | 2.6 ± 1.0 | |
| CD4H/CD4 | 26 655 | 99.3 ± 1.2 | 97.9 ± 2.2 | 83.6 ± 2.7 | 5.4 ± 4.0 |
| 26 710 | 92.9 ± 5.1 | 89.8 ± 7.7 | 87.7 ± 1.6 | 14.8 ± 7.6 | |
ND indicates not done.