Effect of SNP, TRAIL, and SNP plus TRAIL on the colony-forming ability of K562 cells, primary AML blasts, and primary normal BFU-Es and GM-CFUs
| . | Control . | SNP . | TRAIL . | SNP + TRAIL . |
|---|---|---|---|---|
| K562 | 103 ± 13 | 53 ± 7 | 20 ± 5 | 5 ± 3 |
| Sample 1 (AML M2) | 55 | 43 | 25 | 2 |
| Sample 2 (AML M3) | 38 | 29 | 18 | 0 |
| Sample 3 (AML M3) | 49 | 36 | 24 | 11 |
| Normal BFU-E | 107 ± 19 | 66 ± 8 | 75 ± 16 | 41 ± 8 |
| Normal GM-CFU | 146 ± 28 | 78 ± 13 | 139 ± 24 | 79 ± 13 |
| . | Control . | SNP . | TRAIL . | SNP + TRAIL . |
|---|---|---|---|---|
| K562 | 103 ± 13 | 53 ± 7 | 20 ± 5 | 5 ± 3 |
| Sample 1 (AML M2) | 55 | 43 | 25 | 2 |
| Sample 2 (AML M3) | 38 | 29 | 18 | 0 |
| Sample 3 (AML M3) | 49 | 36 | 24 | 11 |
| Normal BFU-E | 107 ± 19 | 66 ± 8 | 75 ± 16 | 41 ± 8 |
| Normal GM-CFU | 146 ± 28 | 78 ± 13 | 139 ± 24 | 79 ± 13 |
Data are expressed as number of colonies, and represent the results of individual experiments (for the primary AML samples) or the means ± SDs of 3 to 5 separate experiments (for K562, BFUE-E, and GM-CFU). In each experiment cells were seeded in triplicate.