PBC harvest parameters
PBC harvest parameter . | G-CSF (arm A) n = 22 . | Chemo + G-CSF (arm B) n = 24 . | Significance 2-sided (95% CI) . |
---|---|---|---|
Peripheral access | 12 (54.5%) | 10 (42%) | 0.38 |
Vascath access | 10 (45.5%) | 14 (58%) | |
Liters blood processed (mean) | 35.7 | 39.96 | 0.42 (− 15, 6.4) |
Time to complete collection (mean) | 5 h, 53 min | 6 h, 21 min | 0.56 (− 2, 1) |
WBC × 108/kg (mean)* | 11.97 | 11.92 | 0.95 (− 1.6, 1.7) |
CD34+ cells × 106/kg* | (n = 17) | (n = 18) | |
Median | 2.5 | 7.2 | 0.004 |
Mean | 3.9 | 11.9 | |
Range | 0.3-12.4 | 0.3-44.8 | |
No. apheresis sessions | |||
1 | 11 (50%) | 12 (50%) | 0.86 |
2 | 10 (46%) | 10 (42%) | |
3 | 1 (4%) | 2 (8%) |
PBC harvest parameter . | G-CSF (arm A) n = 22 . | Chemo + G-CSF (arm B) n = 24 . | Significance 2-sided (95% CI) . |
---|---|---|---|
Peripheral access | 12 (54.5%) | 10 (42%) | 0.38 |
Vascath access | 10 (45.5%) | 14 (58%) | |
Liters blood processed (mean) | 35.7 | 39.96 | 0.42 (− 15, 6.4) |
Time to complete collection (mean) | 5 h, 53 min | 6 h, 21 min | 0.56 (− 2, 1) |
WBC × 108/kg (mean)* | 11.97 | 11.92 | 0.95 (− 1.6, 1.7) |
CD34+ cells × 106/kg* | (n = 17) | (n = 18) | |
Median | 2.5 | 7.2 | 0.004 |
Mean | 3.9 | 11.9 | |
Range | 0.3-12.4 | 0.3-44.8 | |
No. apheresis sessions | |||
1 | 11 (50%) | 12 (50%) | 0.86 |
2 | 10 (46%) | 10 (42%) | |
3 | 1 (4%) | 2 (8%) |
One patient in each arm had fewer than 1 × 106CD34+ cells/kg.
All PBCs harvested were transplanted.