Table 1. Results of marrow enrichment,... | American Society of Hematology

Table 1.

Results of marrow enrichment, engraftment, and survival of dogs given 920 cGy total body irradiation and transduced autologous CD34⁺ cells

Dog no.	CD34 purity (%)	CD34 recovery (%)	% GFP⁺ before infusion	No. cells infused (×10⁶/kg)	Days to granulocytes stable > 500/μL	Days to platelets > 50 000/μL	Status
E668	89	52	94	3.3	Not reached	Not reached	Died after 35 d (infection)
E523	77	52	69	2.2	10	43	Alive > 23 mo after Tx
E695	69	63	ND	2.3	14	59	Alive > 22 mo after Tx
E760	N/A	N/A	83	14.4	19	57	Alive > 11 mo after Tx
E737	88	59	90	1.0	23	76	Euthanized after 9 mo

Dog no.	CD34 purity (%)	CD34 recovery (%)	% GFP⁺ before infusion	No. cells infused (×10⁶/kg)	Days to granulocytes stable > 500/μL	Days to platelets > 50 000/μL	Status
E668	89	52	94	3.3	Not reached	Not reached	Died after 35 d (infection)
E523	77	52	69	2.2	10	43	Alive > 23 mo after Tx
E695	69	63	ND	2.3	14	59	Alive > 22 mo after Tx
E760	N/A	N/A	83	14.4	19	57	Alive > 11 mo after Tx
E737	88	59	90	1.0	23	76	Euthanized after 9 mo

GFP, green fluorescent protein; Tx, transplant; ND, not done; N/A, not applicable.