Expression of VEGF and its receptors in tumor cell lines
Cell line . | Type . | VEGF (pg/106cells)3-150 . | VEGFR-2 (Flk-1) . | VEGFR-1 (Flt-1) . |
---|---|---|---|---|
KS Y-1 | Kaposi sarcoma | + (625) | + | + |
M21 | Melanoma | + (487) | + | + |
A375 | Melanoma | + | + | + |
526 | Melanoma | + | + | + |
Hey | Ovarian carcinoma | + (419) | + | + |
Hoc-7 | Ovarian carcinoma | + (550) | + | + |
Panc-3 | Pancreatic carcinoma | + | + | + |
LNCaP | Prostate carcinoma | + (719) | + | − |
U937 | Promonocytoid | + (1476) | − | + |
HL-60 | Erythroid leukemia | − | − | − |
HuT 78 | T-cell leukemia | − | − | − |
T1 | Fibroblast | − | − | − |
Cell line . | Type . | VEGF (pg/106cells)3-150 . | VEGFR-2 (Flk-1) . | VEGFR-1 (Flt-1) . |
---|---|---|---|---|
KS Y-1 | Kaposi sarcoma | + (625) | + | + |
M21 | Melanoma | + (487) | + | + |
A375 | Melanoma | + | + | + |
526 | Melanoma | + | + | + |
Hey | Ovarian carcinoma | + (419) | + | + |
Hoc-7 | Ovarian carcinoma | + (550) | + | + |
Panc-3 | Pancreatic carcinoma | + | + | + |
LNCaP | Prostate carcinoma | + (719) | + | − |
U937 | Promonocytoid | + (1476) | − | + |
HL-60 | Erythroid leukemia | − | − | − |
HuT 78 | T-cell leukemia | − | − | − |
T1 | Fibroblast | − | − | − |
Cells were cultured for 48 hours. VEGF levels in the supernatants were measured by ELISA.