Table 3. Features of APA-positive... | American Society of Hematology

Table 3.

Features of APA-positive patients

	Group A^3-150	Group B^3-151	P
Number of patients	14	17
Median age, y	37 (20-53)	30 (16-66)	NS
Male/Female	2/12	2/15	NS
Initial platelet count
0-50 × 10⁹	10 (71.4%)	12 (70.5%)	NS
51-100 × 10⁹	3 (21.4%)	5 (29.4%)	NS
101-140 × 10⁹	1 (7.2%)	0	NS
LA positivity	13 (92.8%)	7 (41.1%)	.0036
ACA IgG	n = 12	n = 17
Negative (0-10 GPL)	5 (41.6%)	7 (41.1%)	NS
Low positive (11-19)	2 (16.6%)	6 (35.2%)	NS
Positive (20-59)	2 (16.6%)	2 (0.11%)	NS
High positive (> 60)	3 (25%)	2 (0.11%)
ACA IgM	n = 12	n = 17
Negative (0-10 MPL)	10 (83.3%)	5 (29.4%)	.007
Low positive (11-19)	0	4 (23.5%)	NS
Positive (20-59)	2 (16.6%)	7 (41%)	NS
High positive (> 60)	0	1 (5%)
Response to therapy
No therapy	4 (28.5%)	4 (23.5%)	NS
CR with MP	1 (7.1%)	6 (35.2%)	.09
PR with MP	6 (42.8%)	6 (35.2%)	NS
Splenectomy	3 (21.4%)	1 (5.8%)	NS

	Group A^3-150	Group B^3-151	P
Number of patients	14	17
Median age, y	37 (20-53)	30 (16-66)	NS
Male/Female	2/12	2/15	NS
Initial platelet count
0-50 × 10⁹	10 (71.4%)	12 (70.5%)	NS
51-100 × 10⁹	3 (21.4%)	5 (29.4%)	NS
101-140 × 10⁹	1 (7.2%)	0	NS
LA positivity	13 (92.8%)	7 (41.1%)	.0036
ACA IgG	n = 12	n = 17
Negative (0-10 GPL)	5 (41.6%)	7 (41.1%)	NS
Low positive (11-19)	2 (16.6%)	6 (35.2%)	NS
Positive (20-59)	2 (16.6%)	2 (0.11%)	NS
High positive (> 60)	3 (25%)	2 (0.11%)
ACA IgM	n = 12	n = 17
Negative (0-10 MPL)	10 (83.3%)	5 (29.4%)	.007
Low positive (11-19)	0	4 (23.5%)	NS
Positive (20-59)	2 (16.6%)	7 (41%)	NS
High positive (> 60)	0	1 (5%)
Response to therapy
No therapy	4 (28.5%)	4 (23.5%)	NS
CR with MP	1 (7.1%)	6 (35.2%)	.09
PR with MP	6 (42.8%)	6 (35.2%)	NS
Splenectomy	3 (21.4%)	1 (5.8%)	NS

Abbreviations are explained in Table 1.

APA-positive and APS-positive patients.

APA-positive and APS-negative patients.