Table 3. EBV cell subtype in EBV-HLH and... | American Society of Hematology

Table 3.

EBV cell subtype in EBV-HLH and CAEBV

Patient	Source	EBV subtype
Patient	Source	LMP-1	EBNA-1	EBNA-2
EBV-HLH1	CD8⁺ T cell	Del	P-Ala, V-Val	NA
	sLCL	Del	V-Val	Type A
EBV-HLH2	PBMNC	Del	NA	Type A
	T cell	Del	V-Val	Type A
	Non–T cell	Del	P-Ala, V-Val	Type A
EBV-HLH3	PBMNC	Del	NA	NA
	sLCL	Del	V-Val	Type A
EBV-HLH4	CD8⁺T cell	Del	V-Val	Type A
	CD16⁺ NK cell	Del	P-Ala, V-Val	Type A
	CD20⁺ B cell	Del	V-Val	NA
	sLCL	Del	V-Val	Type A
CAEBV1	CD4⁺ T cell	Del	V-Val	Type A
	CD8⁺ T cell	Del	V-Val	Type A
CAEBV2	PBMNC	Del	V-Val	Type A
	CD16⁺NK cell	Del	V-Val	Type A
CAEBV3	CD4⁺ T cell	Del	V-Val	Type A
	sLCL	Del	V-Val	Type A
CAEBV4	PBMNC	Wild	P-Ala	Type A

Patient	Source	EBV subtype
Patient	Source	LMP-1	EBNA-1	EBNA-2
EBV-HLH1	CD8⁺ T cell	Del	P-Ala, V-Val	NA
	sLCL	Del	V-Val	Type A
EBV-HLH2	PBMNC	Del	NA	Type A
	T cell	Del	V-Val	Type A
	Non–T cell	Del	P-Ala, V-Val	Type A
EBV-HLH3	PBMNC	Del	NA	NA
	sLCL	Del	V-Val	Type A
EBV-HLH4	CD8⁺T cell	Del	V-Val	Type A
	CD16⁺ NK cell	Del	P-Ala, V-Val	Type A
	CD20⁺ B cell	Del	V-Val	NA
	sLCL	Del	V-Val	Type A
CAEBV1	CD4⁺ T cell	Del	V-Val	Type A
	CD8⁺ T cell	Del	V-Val	Type A
CAEBV2	PBMNC	Del	V-Val	Type A
	CD16⁺NK cell	Del	V-Val	Type A
CAEBV3	CD4⁺ T cell	Del	V-Val	Type A
	sLCL	Del	V-Val	Type A
CAEBV4	PBMNC	Wild	P-Ala	Type A

EBV subtype was estimated from DNA isolated from indicated cell populations by PCR methods and sequencing of PCR products.

Del indicates 30-bp deletion at C-terminal of LMP-1; NA, not amplified by PCR; sLCL, spontaneously growing EBV⁺ lymphoblastoid B-cell line.