Table 3.

Gastrointestinal toxicity during induction chemotherapy

ToxicityOverall
(n = 698)
Age (y)P value for trend
0
(n = 57)
1
(n = 95)
2-4
(n = 140)
5-9
(n = 178)
10-15
(n = 228)
Nausea/vomiting 25 25 24 20 19 33 .01  
Oral toxicity 23 24 27 28 15 25 .8 
Diarrhea 19 38 34 15 12 16 .002 
ToxicityOverall
(n = 698)
Age (y)P value for trend
0
(n = 57)
1
(n = 95)
2-4
(n = 140)
5-9
(n = 178)
10-15
(n = 228)
Nausea/vomiting 25 25 24 20 19 33 .01  
Oral toxicity 23 24 27 28 15 25 .8 
Diarrhea 19 38 34 15 12 16 .002 

Percent of patients with WHO scores of 3 or 4 in each age group (higher score indicates worse toxicity). Score is available in at least 90% of each group (except oral toxicity in infants where it is available in 89% of cases).

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